SCHEMBL14799790

SCHEMBL14799790

CC(C)COc1ccc(-c2ccc(-c3ccc(OCC(C)C)cc3)c3nn(-c4ccc(N5C(=O)C6CCCCC6C5=O)cc4)nc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ LMNA P02545 3/20 0.36
▸ MEN1 O00255 2/20 0.36
▸ MAPT P10636 2/20 0.36
▸ HTT P42858 1/20 0.36
▸ MDM2 Q00987 1/20 0.35
▸ MCL1 Q07820 1/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ GAA P10253 2/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ HPGD P15428 1/20 0.34
▸ HRH3 Q9Y5N1 3/20 0.34
▸ XDH P47989 1/20 0.34
▸ POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14800040 0.81 KMT2A (0.48) KMT2AMEN1MAPTMDM2MCL1
SCHEMBL14799893 0.80 POLB (0.40) KMT2ALMNAMEN1MAPTHTT
SCHEMBL14799716 0.78 NPC1 (0.43) KMT2AL3MBTL1LMNAMEN1MAPT
SCHEMBL14806791 0.75 MAPT (0.47) KMT2ALMNAMEN1MAPTHTT
SCHEMBL14799791 0.70 KDM4E (0.44) KMT2ALMNAMEN1MAPTHTT
SCHEMBL14799741 0.69 NPC1 (0.46) KMT2AL3MBTL1LMNAMEN1MAPT
SCHEMBL16401994 0.67 MEN1 (0.42) KMT2ALMNAMEN1MAPTHTT
SCHEMBL11537780 0.66 GAA (0.57) KMT2AL3MBTL1LMNAMEN1MAPT
SCHEMBL16885012 0.64 HPGD (0.47) KMT2ALMNAMEN1MAPTHTT
SCHEMBL14799643 0.64 SMPD1 (0.51) KMT2ALMNAMEN1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY SUN2, NES, CRY1 KMT2A 645/4885L3MBTL1 2873/4885LMNA 792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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