SCHEMBL14800040

SCHEMBL14800040

CC(C)COc1ccc(-c2ccc(-c3ccc(OCC(C)C)cc3)c3nn(-c4ccc(N5C(=O)c6ccccc6C5=O)cc4)nc23)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.48
▸ PLA2G1B P04054 1/20 0.47
▸ ATG4B Q9Y4P1 1/20 0.47
▸ MEN1 O00255 3/20 0.43
▸ NR1H3 Q13133 1/20 0.43
▸ KDM4E B2RXH2 2/20 0.42
▸ ALDH1A1 P00352 2/20 0.42
▸ CYP2D6 P10635 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ MDM2 Q00987 1/20 0.42
▸ MCL1 Q07820 1/20 0.42
▸ PPARD Q03181 1/20 0.41
▸ PPARA Q07869 1/20 0.41
▸ ABCB1 P08183 2/20 0.40
▸ PPARG P37231 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ MAPT P10636 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ RXFP1 Q9HBX9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14799893 0.82 POLB (0.40) KMT2AMEN1KDM4EALDH1A1MDM2
SCHEMBL14799716 0.81 NPC1 (0.43) KMT2AMEN1KDM4EALDH1A1CYP2C9
SCHEMBL14799790 0.81 KMT2A (0.39) KMT2AMEN1ALDH1A1MDM2MCL1
SCHEMBL14806791 0.79 MAPT (0.47) KMT2AMEN1ALDH1A1MDM2MCL1
SCHEMBL14799791 0.75 KDM4E (0.44) KMT2AMEN1KDM4EALDH1A1CYP2C9
SCHEMBL14799741 0.72 NPC1 (0.46) KMT2AMEN1KDM4EALDH1A1CYP2D6
SCHEMBL4726090 0.72 KMT2A (0.61) KMT2APLA2G1BATG4BMEN1NR1H3
SCHEMBL16401994 0.70 MEN1 (0.42) KMT2AMEN1KDM4EALDH1A1CYP2C9
SCHEMBL28527296 0.69 MEN1 (0.42) KMT2AMEN1KDM4EALDH1A1CYP2C9
SCHEMBL11862277 0.69 KDM4E (0.74) KMT2AMEN1NR1H3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY SUN2, NES, CRY1 KMT2A 645/4885PLA2G1B 4437/4885ATG4B 1186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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