Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14799810 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTHSP90AA1HPGDGFER | |
| SCHEMBL15439271 | 0.85 | CES2 (0.50) | MAPTHPGDGAACYP2C19RAB9A | |
| SCHEMBL15439968 | 0.85 | CES2 (0.48) | ALDH1A1MAPTHPGDGAACYP2C19 | |
| SCHEMBL15439969 | 0.85 | CES2 (0.48) | ALDH1A1MAPTHPGDGAACYP2C19 | |
| SCHEMBL15439272 | 0.85 | CES2 (0.50) | MAPTHPGDGAACYP2C19RAB9A | |
| SCHEMBL10498731 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTHSP90AA1HPGDGFER | |
| SCHEMBL7373897 | 0.78 | G6PC1 (0.57) | ALDH1A1MAPTHSP90AA1HPGDGFER | |
| SCHEMBL14667522 | 0.78 | G6PC1 (0.57) | ALDH1A1MAPTHSP90AA1HPGDGFER | |
| SCHEMBL2615559 | 0.78 | G6PC1 (0.57) | ALDH1A1MAPTHSP90AA1HPGDGFER | |
| SCHEMBL14799744 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPTHSP90AA1HPGDGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | claimed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | claimed |
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | disclosed |