SCHEMBL14799902

SCHEMBL14799902

CCCCCC(=O)Nc1ccc(-n2nc3c(-c4ccc(N(c5ccccc5)c5ccccc5)cc4)ccc(-c4ccc(N(c5ccccc5)c5ccccc5)cc4)c3n2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.47
▸ SMN1; SMN2 Q16637 3/20 0.47
▸ SOAT1 P35610 5/20 0.45
▸ SOAT2 O75908 3/20 0.45
▸ RAB9A P51151 5/20 0.44
▸ GAA P10253 3/20 0.44
▸ NAMPT P43490 2/20 0.44
▸ NPC1 O15118 2/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ POLB P06746 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ ALDH1A1 P00352 5/20 0.44
▸ RORC P51449 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ GLA P06280 1/20 0.43
▸ LMNA P02545 2/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ RORA P35398 1/20 0.43
▸ NR1H4 Q96RI1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14806797 0.94 L3MBTL1 (0.43) MAPTSMN1; SMN2RAB9AGAANPC1
SCHEMBL14806802 0.92 SMN1; SMN2 (0.40) MAPTSMN1; SMN2RAB9AGAANPC1
SCHEMBL14806804 0.78 LTB4R2 (0.39) SMN1; SMN2L3MBTL1HPGD
SCHEMBL14799741 0.77 NPC1 (0.46) MAPTSMN1; SMN2RAB9AGAANPC1
SCHEMBL14806808 0.76 LTB4R2 (0.41) SMN1; SMN2GAAKMT2AKDM4EL3MBTL1
SCHEMBL23833672 0.76 MAPT (0.43) MAPTSMN1; SMN2
SCHEMBL23833674 0.76 SMN1; SMN2 (0.43) MAPTSMN1; SMN2ALDH1A1LMNA
SCHEMBL7024489 0.75 HDAC3 (0.66) SMN1; SMN2SOAT1SOAT2RAB9ANAMPT
SCHEMBL14806809 0.74 MAPKAPK2 (0.36) SMN1; SMN2L3MBTL1HPGD
SCHEMBL11694913 0.72 HDAC8 (0.75) SMN1; SMN2SOAT1SOAT2RAB9ANAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY SUN2, NES, CRY1 MAPT 1709/4885SMN1; SMN2 2766/4885SOAT1 1581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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