SCHEMBL1480129

SCHEMBL1480129

O=C1c2ccccc2-c2cc(-c3ccc(C(F)(F)F)cc3)ccc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.62
NPC1 O15118 2/20 0.62
RAB9A P51151 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
MEN1 O00255 2/20 0.62
LMNA P02545 2/20 0.62
HTT P42858 2/20 0.62
KMT2A Q03164 2/20 0.62
APAF1 O14727 1/20 0.62
THRB P10828 1/20 0.62
XBP1 P17861 1/20 0.62
PTBP1 P26599 1/20 0.62
GALK1 P51570 1/20 0.62
BLM P54132 1/20 0.62
SMAD3 P84022 1/20 0.62
ATM Q13315 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
MAOB P27338 2/20 0.57
KIF11 P52732 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1480615 0.97 MAPT (0.58) MAPTNPC1RAB9AL3MBTL1MEN1
SCHEMBL30689243 0.89 TDP2 (0.53) MAPTNPC1RAB9AL3MBTL1MEN1
SCHEMBL1481010 0.89 TDP2 (0.53) MAPTNPC1RAB9AL3MBTL1MEN1
SCHEMBL28626995 0.85 NPC1 (0.58) MAPTNPC1RAB9AL3MBTL1MEN1
SCHEMBL7791837 0.82 NPC1 (0.63) MAPTNPC1RAB9AL3MBTL1MEN1
SCHEMBL31674878 0.82 NPC1 (0.63) MAPTNPC1RAB9AL3MBTL1MEN1
SCHEMBL978978 0.81 NPC1 (0.92) MAPTNPC1RAB9AL3MBTL1MEN1
SCHEMBL9171969 0.80 NPC1 (0.66) MAPTNPC1RAB9AL3MBTL1MEN1
SCHEMBL13292064 0.78 NPC1 (0.58) MAPTNPC1RAB9AL3MBTL1MEN1
SCHEMBL15383587 0.77 MEN1 (1.00) MAPTNPC1RAB9AL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293856-B2 Process for preparing olefin polymer using mixed catalyst MITSUI CHEMICALS, INC. (JP) 2012-10-23 US disclosed
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed