SCHEMBL978978

SCHEMBL978978

O=C1c2ccccc2-c2cc(-c3ccccc3)ccc21

nearest known ligand 0.92

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.92
RAB9A P51151 4/20 0.92
SMN1; SMN2 Q16637 4/20 0.92
MEN1 O00255 3/20 0.92
KMT2A Q03164 3/20 0.92
MAPT P10636 3/20 0.92
APAF1 O14727 2/20 0.92
LMNA P02545 2/20 0.92
THRB P10828 2/20 0.92
HTT P42858 2/20 0.92
GALK1 P51570 2/20 0.92
BLM P54132 2/20 0.92
NPSR1 Q6W5P4 2/20 0.92
XBP1 P17861 1/20 0.92
PTBP1 P26599 1/20 0.92
SMAD3 P84022 1/20 0.92
ATM Q13315 1/20 0.92
L3MBTL1 Q9Y468 1/20 0.92
PTPRC P08575 7/20 0.53
PTPN1 P18031 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15383587 0.96 MEN1 (1.00) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL7322266 0.96 MEN1 (0.84) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL1482692 0.96 MEN1 (0.84) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL18073335 0.96 NPC1 (0.83) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL30719688 0.96 NPC1 (0.83) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL30722379 0.93 NPC1 (0.80) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL21993324 0.93 NPC1 (0.80) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL57813 0.93 NPC1 (0.80) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL19001850 0.92 NPC1 (0.78) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL19001853 0.92 NPC1 (0.78) NPC1RAB9ASMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390365-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-04-14 EP disclosed
US-9859502-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2018-01-02 US disclosed
WO-2017102063-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-06-22 WO disclosed
US-20160268509-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-09-15 US disclosed
US-20160268509-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-09-15 US disclosed
EP-1739485-B1 RESIST COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2016-08-31 EP disclosed
US-7871751-B2 Resist composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-01-18 US disclosed
CN-1942825-B Resist composition MITSUBISHI GAS CHEMICAL CO 2010-05-12 CN disclosed
US-20080153031-A1 Resist composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-06-26 US disclosed
CN-1942825-A Resist composition MITSUBISHI GAS CHEMICAL CO (JP) 2007-04-04 CN disclosed
EP-1739485-A1 RESIST COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-01-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160268509-A1 MATERIALS FOR ELECTRONIC DEVICES EFNA1, GPX1, EPN1 NPC1 2849/4885RAB9A 1636/4885SMN1; SMN2 3457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.