SCHEMBL30689243

SCHEMBL30689243

O=C1c2cc(-c3ccc(C(F)(F)F)cc3)ccc2-c2ccc(-c3ccc(C(F)(F)F)cc3)cc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 1/20 0.53
KIF11 P52732 17/20 0.49
MAOB P27338 1/20 0.47
MEN1 O00255 1/20 0.46
APAF1 O14727 1/20 0.46
NPC1 O15118 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46
XBP1 P17861 1/20 0.46
PTBP1 P26599 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
GALK1 P51570 1/20 0.46
BLM P54132 1/20 0.46
SMAD3 P84022 1/20 0.46
KMT2A Q03164 1/20 0.46
ATM Q13315 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1481010 1.00 TDP2 (0.53) TDP2KIF11MAOBMEN1APAF1
SCHEMBL1480615 0.93 MAPT (0.58) TDP2KIF11MAOBMEN1APAF1
SCHEMBL1480129 0.89 MAPT (0.62) TDP2KIF11MAOBMEN1APAF1
SCHEMBL10050482 0.86 RXRA (0.49) TDP2MAOBMEN1APAF1NPC1
SCHEMBL21741046 0.84 TDP2 (0.47) TDP2KIF11MAPT
SCHEMBL30689245 0.83 PARP10 (0.55) KIF11MAOBMEN1APAF1NPC1
SCHEMBL18528794 0.83 NPC1 (0.50) TDP2MAOBNPC1LMNARAB9A
SCHEMBL14252248 0.79 TDP2 (0.53) TDP2KIF11MAOBMEN1MAPT
SCHEMBL13292063 0.79 PARP1 (0.46) TDP2NPC1LMNARAB9AATM
SCHEMBL1479862 0.77 PTPRC (0.50) MAOBMEN1APAF1NPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117209367-A Fluorenyl bisphenol monomer and fluorenyl polyarylether resin, and preparation method and application thereof 大连理工大学 2023-12-12 CN claimed
CN-117209367-A Fluorenyl bisphenol monomer and fluorenyl polyarylether resin, and preparation method and application thereof 大连理工大学 2023-12-12 CN disclosed