SCHEMBL14801671

SCHEMBL14801671

O=C(C=Cc1ccccc1)Nc1cc(O)ccc1C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PELI1 Q96FA3 1/20 0.68
TRPM2 O94759 3/20 0.64
LTB4R Q15722 1/20 0.64
TRPA1 O75762 5/20 0.63
TRPM8 Q7Z2W7 2/20 0.63
MAPT P10636 4/20 0.62
MMP1 P03956 7/20 0.60
MMP2 P08253 7/20 0.60
MMP9 P14780 7/20 0.60
DEGS1 O15121 1/20 0.60
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
KDM4E B2RXH2 1/20 0.58
ALDH1A1 P00352 1/20 0.58
CYP3A4 P08684 1/20 0.58
THRB P10828 1/20 0.58
HPGD P15428 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31153395 1.00 PELI1 (0.68) PELI1TRPM2LTB4RTRPA1TRPM8
SCHEMBL9973825 0.93 TRPM2 (0.62) PELI1TRPM2LTB4RTRPA1TRPM8
SCHEMBL9973838 0.92 MMP1 (0.65) PELI1MAPTMMP1MMP2MMP9
SCHEMBL4670106 0.90 TRPM2 (0.64) PELI1TRPM2LTB4RTRPA1TRPM8
SCHEMBL6013326 0.90 TRPM2 (0.64) PELI1TRPM2LTB4RTRPA1TRPM8
SCHEMBL2271170 0.89 TRPM2 (0.70) PELI1TRPM2LTB4RTRPA1TRPM8
SCHEMBL2271172 0.89 TRPM2 (0.70) PELI1TRPM2LTB4RTRPA1TRPM8
SCHEMBL294403 0.86 TRPM2 (0.83) TRPM2LTB4RTRPA1TRPM8MAPT
SCHEMBL294402 0.86 TRPM2 (0.83) TRPM2LTB4RTRPA1TRPM8MAPT
SCHEMBL2274109 0.85 TRPM2 (0.76) TRPM2LTB4RTRPA1TRPM8MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10280441-B2 Host cells and methods for producing cinnamoyl anthranilate and analogs thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-05-07 US disclosed
US-20130078683-A1 Host Cells and Methods for Producing Cinnamoyl Anthranilate and Analogs Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-03-28 US disclosed