SCHEMBL6013326

SCHEMBL6013326

O=C(C=Cc1ccccc1)Nc1ccc(O)cc1C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPM2 O94759 2/20 0.64
MAPT P10636 3/20 0.64
PELI1 Q96FA3 1/20 0.62
LTB4R Q15722 1/20 0.62
GAA P10253 1/20 0.62
MMP1 P03956 7/20 0.61
MMP2 P08253 7/20 0.61
MMP9 P14780 7/20 0.61
DEGS1 O15121 1/20 0.61
TRPA1 O75762 5/20 0.60
TRPM8 Q7Z2W7 2/20 0.60
EGFR P00533 2/20 0.58
MEN1 O00255 1/20 0.56
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
KMT2A Q03164 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4670106 1.00 TRPM2 (0.64) TRPM2MAPTPELI1LTB4RGAA
SCHEMBL29913807 0.93 TRPM2 (0.62) TRPM2MAPTPELI1LTB4RMMP1
SCHEMBL4670083 0.93 TRPM2 (0.62) TRPM2MAPTPELI1LTB4RMMP1
SCHEMBL5351229 0.93 TRPM2 (0.62) TRPM2MAPTPELI1LTB4RMMP1
SCHEMBL9973836 0.92 MMP1 (0.67) MAPTPELI1MMP1MMP2MMP9
SCHEMBL14801671 0.90 PELI1 (0.68) TRPM2MAPTPELI1LTB4RGAA
SCHEMBL31153395 0.90 PELI1 (0.68) TRPM2MAPTPELI1LTB4RGAA
SCHEMBL18230842 0.87 TRPM2 (0.64) TRPM2MAPTLTB4RGAAMMP1
SCHEMBL27478826 0.87 MAPT (0.73) TRPM2MAPTLTB4RGAAMMP1
SCHEMBL8060454 0.86 EGFR (0.75) TRPM2MAPTLTB4RGAAMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006117602-A2 USE OF AMIDE DERIVATIVES AS TASTE-MODIFYING AGENTS, FLAVOURING COMPOSITIONS AND PRODUCTS CONTAINING THEM UNIVERSITA' DEGLI STUDI DI MILANO (IT) 2006-11-09 WO claimed
US-10280441-B2 Host cells and methods for producing cinnamoyl anthranilate and analogs thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-05-07 US disclosed
US-20130078683-A1 Host Cells and Methods for Producing Cinnamoyl Anthranilate and Analogs Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-03-28 US disclosed