SCHEMBL14801809

SCHEMBL14801809

Oc1cccc(I)c1-c1c(O)cccc1I

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 6/20 0.45
HSD17B10 Q99714 6/20 0.45
TDP1 Q9NUW8 6/20 0.45
RECQL P46063 6/20 0.45
ALDH1A1 P00352 5/20 0.45
HPGD P15428 5/20 0.45
CA2 P00918 4/20 0.45
LMNA P02545 3/20 0.45
CA1 P00915 3/20 0.45
EGFR P00533 2/20 0.45
FYN P06241 2/20 0.45
MMP9 P14780 2/20 0.45
ADAMTS4 O75173 1/20 0.45
MMP2 P08253 1/20 0.45
MMP8 P22894 1/20 0.45
CA6 P23280 1/20 0.45
CDK2 P24941 1/20 0.45
MMP12 P39900 1/20 0.45
ADAMTS5 Q9UNA0 1/20 0.45
MAOA P21397 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9564314 0.86 TSHR (0.48) ALOX15HSD17B10TDP1RECQLALDH1A1
SCHEMBL17448425 0.86 TRPA1 (0.48) ALOX15HSD17B10TDP1RECQLALDH1A1
SCHEMBL11267122 0.84 TSHR (0.46) ALOX15HSD17B10TDP1RECQLALDH1A1
SCHEMBL5918581 0.77 ALOX15 (0.60) ALOX15HSD17B10TDP1RECQLALDH1A1
SCHEMBL20721741 0.77 TDP2 (0.39) IDO1
SCHEMBL605558 0.77
SCHEMBL30309717 0.77
SCHEMBL29455324 0.77
SCHEMBL512801 0.77
SCHEMBL5720 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2760940-A1 THERMOCHROMIC COMPOSITIONS FROM TRISUBSTITUTED PYRIDINE LEUCO DYES Chromatic Technologies, Inc. (US) 2014-08-06 EP claimed
WO-2013049229-A1 THERMOCHROMIC COMPOSITIONS FROM TRISUBSTITUTED PYRIDINE LEUCO DYES CHROMATIC TECHNOLOGIES, INC. (US) 2013-04-04 WO claimed
US-20130075675-A1 Thermochromic Compositions From Trisubstituted Pyridine Leuco Dyes CHROMATIC TECHNOLOGIES, INC. (US) 2013-03-28 US claimed
EP-2970677-B1 SMALL SCALE MICROENCAPSULATED PIGMENTS AND USES THEREOF CHROMATIC TECH INC (US) 2018-11-21 EP disclosed
US-9695320-B2 Small scale microencapsulated pigments and uses thereof CHROMATIC TECHNOLOGIES, INC. (US) 2017-07-04 US disclosed
US-20160083586-A1 Small Scale Microencapsulated Pigments And Uses Thereof CHROMATIC TECHNOLOGIES, INC. (US) 2016-03-24 US disclosed
EP-2970677-A2 SMALL SCALE MICROENCAPSULATED PIGMENTS AND USES THEREOF Chromatic Technologies, Inc. (US) 2016-01-20 EP disclosed
US-9175175-B2 Small scale microencapsulated pigments and uses thereof CHROMATIC TECHNOLOGIES, INC. (US) 2015-11-03 US disclosed
US-20150076423-A1 SMALL SCALE MICROENCAPSULATED PIGMENTS AND USES THEREOF CHROMATIC TECHNOLOGIES, INC. 2015-03-19 US disclosed
EP-2809733-A1 THERMOCHROMIC SYSTEMS WITH CONTROLLED HYSTERESIS Chromatic Technologies, Inc. (US) 2014-12-10 EP disclosed
US-8883049-B2 Small scale microencapsulated pigments and uses thereof CHROMATIC TECHNOLOGIES, INC. (US) 2014-11-11 US disclosed
US-20140272161-A1 SMALL SCALE MICROENCAPSULATED PIGMENTS AND USES THEREOF CHROMATIC TECHNOLOGIES, INC. (US) 2014-09-18 US disclosed
WO-2014144853-A2 SMALL SCALE MICROENCAPSULATED PIGMENTS AND USES THEREOF CHROMATIC TECHNOLOGIES INC. (US) 2014-09-18 WO disclosed
EP-2760940-A1 THERMOCHROMIC COMPOSITIONS FROM TRISUBSTITUTED PYRIDINE LEUCO DYES Chromatic Technologies, Inc. (US) 2014-08-06 EP disclosed
WO-2013115800-A1 THERMOCHROMIC SYSTEMS WITH CONTROLLED HYSTERESIS CHROMATIC TECHNOLOGIES, INC. (US) 2013-08-08 WO disclosed
US-20130193386-A1 THERMOCHROMIC SYSTEMS WITH CONTROLLED HYSTERESIS CHROMATIC TECHNOLOGIES, INC. 2013-08-01 US disclosed
WO-2013049229-A1 THERMOCHROMIC COMPOSITIONS FROM TRISUBSTITUTED PYRIDINE LEUCO DYES CHROMATIC TECHNOLOGIES, INC. (US) 2013-04-04 WO disclosed
US-20130075675-A1 Thermochromic Compositions From Trisubstituted Pyridine Leuco Dyes CHROMATIC TECHNOLOGIES, INC. (US) 2013-03-28 US disclosed