SCHEMBL14801976

SCHEMBL14801976

COc1ccc(OC)c(C=CC(=O)Nc2ccccc2C(=O)O)c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.76
TRPM8 Q7Z2W7 2/20 0.76
KMT2A Q03164 9/20 0.69
MEN1 O00255 8/20 0.69
MAPT P10636 6/20 0.69
NPC1 O15118 3/20 0.69
RAB9A P51151 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
ALDH1A1 P00352 7/20 0.68
KDM4E B2RXH2 4/20 0.68
TP53 P04637 2/20 0.68
CYP3A4 P08684 2/20 0.68
HPGD P15428 2/20 0.68
HIF1A Q16665 2/20 0.68
NFKB1 P19838 2/20 0.68
PDE4D Q08499 2/20 0.68
CYP1A2 P05177 1/20 0.68
CYP2C9 P11712 1/20 0.68
CYP2C19 P33261 1/20 0.68
HSD17B10 Q99714 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2781354 0.91 TRPA1 (0.76) TRPA1TRPM8KMT2AMEN1MAPT
SCHEMBL2781352 0.91 TRPA1 (0.76) TRPA1TRPM8KMT2AMEN1MAPT
SCHEMBL8636778 0.90 TRPA1 (0.61) TRPA1TRPM8KMT2AMEN1MAPT
SCHEMBL8636769 0.90 TRPA1 (0.61) TRPA1TRPM8KMT2AMEN1MAPT
SCHEMBL8060572 0.87 TRPA1 (1.00) TRPA1TRPM8KMT2AMEN1MAPT
SCHEMBL8060574 0.87 TRPA1 (1.00) TRPA1TRPM8KMT2AMEN1MAPT
SCHEMBL20455926 0.86 TRPA1 (0.69) TRPA1TRPM8KMT2AMEN1MAPT
SCHEMBL14801855 0.83 NFKB1 (0.53) TRPA1TRPM8KMT2AMEN1MAPT
SCHEMBL13320675 0.82 TRPA1 (0.74) TRPA1TRPM8KMT2AMEN1MAPT
SCHEMBL2779698 0.82 TRPA1 (0.78) TRPA1TRPM8KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10280441-B2 Host cells and methods for producing cinnamoyl anthranilate and analogs thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-05-07 US disclosed
US-20130078683-A1 Host Cells and Methods for Producing Cinnamoyl Anthranilate and Analogs Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-03-28 US disclosed