SCHEMBL14802124

SCHEMBL14802124

CCCCCOc1cc(-c2ccccc2)nc(-c2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.53
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP19A1 P11511 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
KDM4E B2RXH2 1/20 0.50
NPC1 O15118 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ATP4A P20648 3/20 0.48
ATP4B P51164 3/20 0.48
PLA2G2A P14555 1/20 0.48
DHODH Q02127 1/20 0.48
SOAT1 P35610 1/20 0.48
TLR8 Q9NR97 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14801927 0.88 CYP2D6 (0.57) LTA4HCYP1A2CYP2D6CYP19A1CYP2C9
SCHEMBL13952547 0.84 XDH (0.51) LTA4HCYP1A2CYP2D6CYP19A1CYP2C9
SCHEMBL8271637 0.82 NPC1 (0.58) LTA4HKDM4ENPC1ALDH1A1MAPT
SCHEMBL8619946 0.81 LTA4H (0.48) LTA4HCYP1A2CYP2D6CYP19A1CYP2C9
SCHEMBL9676963 0.80 CYP1A2 (0.59) LTA4HCYP1A2CYP2D6CYP19A1CYP2C9
SCHEMBL7784900 0.80 CYP1A2 (0.59) LTA4HCYP1A2CYP2D6CYP19A1CYP2C9
SCHEMBL7110386 0.80 LTB4R (0.68)
SCHEMBL21988539 0.79 CYP2D6 (0.65) LTA4HCYP1A2CYP2D6CYP19A1CYP2C9
SCHEMBL28113169 0.79 CYP2D6 (0.62) LTA4HCYP1A2CYP2D6CYP19A1CYP2C9
Hydrochloric Acid SCHEMBL9679292 0.78 CYP1A2 (0.57) LTA4HCYP1A2CYP2D6CYP19A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970677-B1 SMALL SCALE MICROENCAPSULATED PIGMENTS AND USES THEREOF CHROMATIC TECH INC (US) 2018-11-21 EP disclosed
US-9695320-B2 Small scale microencapsulated pigments and uses thereof CHROMATIC TECHNOLOGIES, INC. (US) 2017-07-04 US disclosed
US-20160083586-A1 Small Scale Microencapsulated Pigments And Uses Thereof CHROMATIC TECHNOLOGIES, INC. (US) 2016-03-24 US disclosed
US-9175175-B2 Small scale microencapsulated pigments and uses thereof CHROMATIC TECHNOLOGIES, INC. (US) 2015-11-03 US disclosed
US-20150076423-A1 SMALL SCALE MICROENCAPSULATED PIGMENTS AND USES THEREOF CHROMATIC TECHNOLOGIES, INC. 2015-03-19 US disclosed
US-8883049-B2 Small scale microencapsulated pigments and uses thereof CHROMATIC TECHNOLOGIES, INC. (US) 2014-11-11 US disclosed
US-20140272161-A1 SMALL SCALE MICROENCAPSULATED PIGMENTS AND USES THEREOF CHROMATIC TECHNOLOGIES, INC. (US) 2014-09-18 US disclosed
EP-2760940-A1 THERMOCHROMIC COMPOSITIONS FROM TRISUBSTITUTED PYRIDINE LEUCO DYES Chromatic Technologies, Inc. (US) 2014-08-06 EP disclosed
US-20130193386-A1 THERMOCHROMIC SYSTEMS WITH CONTROLLED HYSTERESIS CHROMATIC TECHNOLOGIES, INC. 2013-08-01 US disclosed
WO-2013049229-A1 THERMOCHROMIC COMPOSITIONS FROM TRISUBSTITUTED PYRIDINE LEUCO DYES CHROMATIC TECHNOLOGIES, INC. (US) 2013-04-04 WO disclosed
US-20130075675-A1 Thermochromic Compositions From Trisubstituted Pyridine Leuco Dyes CHROMATIC TECHNOLOGIES, INC. (US) 2013-03-28 US disclosed