SCHEMBL1480245

SCHEMBL1480245

COc1ccc(-c2cccc3c2-c2ccccc2C3)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.50
ABCB1 P08183 1/20 0.50
BCR P11274 1/20 0.50
HDAC4 P56524 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
KDM4E B2RXH2 3/20 0.44
MAPT P10636 3/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 2/20 0.44
MAPK1 P28482 2/20 0.44
PKM P14618 2/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
TSHR P16473 1/20 0.44
CYP2C19 P33261 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31282860 0.81 ALDH1A1 (0.43) KDM4EMAPTALDH1A1HPGDMAPK1
SCHEMBL27899659 0.80 MAOA (0.43) KDM4EMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL6828592 0.80 ABL1 (0.50) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL313560 0.80 MAOA (0.46) KDM4EMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL4385698 0.80 ABL1 (0.46) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL22150253 0.77 CNR1 (0.44) TP53SMN1; SMN2HTR1AHTR7NPC1
SCHEMBL9766597 0.77 POLB (0.35) HDAC4HDAC2HDAC8
SCHEMBL11096265 0.77 ABL1 (0.58) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL1480944 0.77 ALDH1A1 (0.56) ABL1ABCB1BCRKDM4EMAPT
SCHEMBL12715050 0.75 ABL1 (0.79) ABL1ABCB1BCRHDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293856-B2 Process for preparing olefin polymer using mixed catalyst MITSUI CHEMICALS, INC. (JP) 2012-10-23 US disclosed
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed