SCHEMBL14804345

SCHEMBL14804345

CC1(C)OB(c2cccc(C3(c4cccc(B5OC(C)(C)C(C)(C)O5)c4)Cc4ccccc4-c4ccccc4C3)c2)OC1(C)C

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 9/20 0.41
LPL P06858 8/20 0.41
ROCK1 Q13464 1/20 0.40
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
BACE1 P56817 1/20 0.37
UTS2R Q9UKP6 2/20 0.33
IRAK4 Q9NWZ3 1/20 0.32
PRNP P04156 1/20 0.32
PPARG P37231 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
NCOR2 Q9Y618 1/20 0.32
P4HB P07237 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14804336 0.84 LPL (0.50) LIPGLPLROCK1PRMT5WDR77
SCHEMBL18593668 0.80 LIPG (0.43) LIPGLPLROCK1BACE1IRAK4
SCHEMBL18547622 0.76 LIPG (0.39) LIPGLPLROCK1BACE1IRAK4
SCHEMBL12166505 0.75 LIPG (0.43) LIPGLPLROCK1PRMT5WDR77
SCHEMBL14595522 0.74 LPL (0.45) LIPGLPLROCK1PRMT5WDR77
SCHEMBL239821 0.74 LIPG (0.42) LIPGLPLROCK1PRMT5WDR77
SCHEMBL18164696 0.74 LPL (0.47) LIPGLPLROCK1PRMT5WDR77
SCHEMBL30079660 0.74 LPL (0.47) LIPGLPLROCK1PRMT5WDR77
SCHEMBL29265 0.74 LPL (0.47) LIPGLPLROCK1PRMT5WDR77
SCHEMBL20109565 0.74 LIPG (0.47) LIPGLPLROCK1PRMT5WDR77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130075714-A1 POLYMER, POLYMER COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE SUMTOMO CHEMICAL COMPANY LIMITED (JP) 2013-03-28 US disclosed
US-20130075714-A1 POLYMER, POLYMER COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE SUMTOMO CHEMICAL COMPANY LIMITED (JP) 2013-03-28 US disclosed