SCHEMBL29265

SCHEMBL29265

CC1(C)OB(c2ccc3c(c2)Cc2ccccc2-3)OC1(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 7/20 0.47
LIPG Q9Y5X9 7/20 0.47
ALDH1A1 P00352 2/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
KDM4E B2RXH2 1/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45
ROCK1 Q13464 1/20 0.43
SRD5A2 P31213 1/20 0.41
CYP1A2 P05177 3/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ADRA2A P08913 1/20 0.40
MAOA P21397 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30079660 1.00 LPL (0.47) LPLLIPGALDH1A1NPC1RAB9A
SCHEMBL20109565 0.94 LIPG (0.47) LPLLIPGALDH1A1NPC1RAB9A
SCHEMBL30860136 0.92 LIPG (0.46) LPLLIPGROCK1BACE1
SCHEMBL202622 0.92 LIPG (0.46) LPLLIPGROCK1BACE1
SCHEMBL22106330 0.88 LPL (0.38) LPLLIPGALDH1A1NPC1RAB9A
SCHEMBL22841974 0.86 MAOA (0.45) LPLLIPGALDH1A1NPC1RAB9A
SCHEMBL18164696 0.84 LPL (0.47) LPLLIPGROCK1BACE1PRMT5
SCHEMBL23767233 0.84 LPL (0.44) LPLLIPGNPC1RAB9AROCK1
SCHEMBL29851996 0.84 PGR (0.41) LPLLIPGROCK1CYP1A2HTR2C
SCHEMBL23294440 0.84 PGR (0.41) LPLLIPGROCK1CYP1A2HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11345717-B2 Detection method THE UNIVERSITY OF QUEENSLAND (AU) 2022-05-31 US claimed
EP-3661942-A1 DETECTION METHOD The University of Queensland (AU) 2020-06-10 EP claimed
US-20200172561-A1 DETECTION METHOD THE UNIVERSITY OF QUEENSLAND (AU) 2020-06-04 US claimed
WO-2019023753-A1 DETECTION METHOD THE UNIVERSITY OF QUEENSLAND (AU) 2019-02-07 WO claimed
CN-118271338-A Organic compound, application thereof and organic electroluminescent device 北京绿人科技有限责任公司 2024-07-02 CN disclosed
CN-117865950-A Synthesis and application of strong D-A type organic near infrared two-region luminescent material 桂林理工大学 2024-04-12 CN disclosed
US-11806335-B2 Heterocyclic carboxylate compounds as glycolate oxidase inhibitors Lilac Therapeutics, Inc. (US) 2023-11-07 US disclosed
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed
CN-113896736-B Aryl-substituted spirooxazine photochromic compound and preparation method and application thereof 南开大学 2023-03-03 CN disclosed
US-11345717-B2 Detection method THE UNIVERSITY OF QUEENSLAND (AU) 2022-05-31 US disclosed
CN-113896736-A Aryl-substituted spirooxazine photochromic compound and preparation method and application thereof 南开大学 2022-01-07 CN disclosed
EP-3661942-A1 DETECTION METHOD The University of Queensland (AU) 2020-06-10 EP disclosed
US-8940414-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2015-01-27 US disclosed
US-8877352-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-11-04 US disclosed
US-8809063-B2 Fluorescent carbazole oligomers nanofibril materials for vapor sensing UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2014-08-19 US disclosed
US-20130217139-A1 FLUORESCENT CARBAZOLE OLIGOMERS NANOFIBRIL MATERIALS FOR VAPOR SENSING NATIONAL SCIENCE FOUNDATION 2013-08-22 US disclosed
US-20120138911-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2012-06-07 US disclosed
WO-2012025760-A1 PROCESS FOR THE BORYLATION OF ARENES AND HETEROARYLS THE UNIVERSITY OF MANCHESTER (GB) 2012-03-01 WO disclosed
WO-2012025760-A1 PROCESS FOR THE BORYLATION OF ARENES AND HETEROARYLS THE UNIVERSITY OF MANCHESTER (GB) 2012-03-01 WO disclosed
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172561-A1 DETECTION METHOD GPX4, HAO2, PPOX LPL 3007/4885LIPG 637/4885ALDH1A1 1863/4885
US-20120138911-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L LPL 4857/4885LIPG 4816/4885ALDH1A1 362/4885
US-11806335-B2 Heterocyclic carboxylate compounds as glycolate oxidase inhibitors UGDH, PGD, PNPO LPL 660/4885LIPG 197/4885ALDH1A1 184/4885
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L LPL 4857/4885LIPG 4816/4885ALDH1A1 362/4885
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE PIEZO1, LEF1, L1CAM LPL 1982/4885LIPG 1679/4885ALDH1A1 254/4885
US-11345717-B2 Detection method GPX4, PPOX, HAO2 LPL 2933/4885LIPG 609/4885ALDH1A1 1702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.