Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 8/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.42 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.42 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.42 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22146594 | 0.95 | RAPGEF4 (0.45) | RAPGEF4CA2LPLLIPGORAI1 | |
| SCHEMBL85680 | 0.90 | RAPGEF4 (0.42) | RAPGEF4CA2LPLLIPGORAI1 | |
| SCHEMBL25129960 | 0.86 | RAPGEF4 (0.37) | RAPGEF4CA2LPLLIPGORAI1 | |
| SCHEMBL22872051 | 0.85 | RAPGEF4 (0.50) | RAPGEF4CA2FFAR4CYP2A6ALDH1A1 | |
| SCHEMBL26720456 | 0.84 | RAPGEF4 (0.37) | RAPGEF4CA2LPLLIPGORAI1 | |
| SCHEMBL85808 | 0.84 | RAPGEF4 (0.37) | RAPGEF4CA2LPLLIPGORAI1 | |
| SCHEMBL7458255 | 0.84 | RAPGEF4 (0.37) | RAPGEF4CA2LPLLIPGORAI1 | |
| SCHEMBL24820988 | 0.84 | FFAR4 (0.46) | RAPGEF4ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL23150833 | 0.80 | FFAR4 (0.44) | RAPGEF4ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL16051086 | 0.80 | ACHE (0.42) | RAPGEF4ACHETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8981354-B2 | Organic light-emitting polymer and device | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2015-03-17 | — | — | US | disclosed |
| US-20130146852-A1 | ORGANIC LIGHT-EMITTING POLYMER AND DEVICE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-06-13 | — | — | US | disclosed |
| US-20130075714-A1 | POLYMER, POLYMER COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE | SUMTOMO CHEMICAL COMPANY LIMITED (JP) | 2013-03-28 | — | — | US | disclosed |