SCHEMBL14809673

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14809866	0.84	L3MBTL1 (0.42)	MAPK8VEGFAEGLN1MAPTTP53
	SCHEMBL14810125	0.83	MAPK8 (0.46)	MAPK8VEGFAEGLN1TP53
	SCHEMBL14809540	0.82	EGLN1 (0.39)	MAPK8VEGFAEGLN1MAPTTP53
	SCHEMBL14810395	0.82	MAPK8 (0.46)	MAPK8EGLN1
	SCHEMBL14823818	0.81	ALOX5 (0.42)	VEGFAEGLN1MAPTTP53MEN1
	SCHEMBL14809449	0.81	MAPT (0.43)	VEGFAEGLN1MAPTTP53MEN1
	SCHEMBL14809783	0.79	EGLN1 (0.36)	MAPK8VEGFAEGLN1MAPTTP53
	SCHEMBL14809136	0.77	MAPT (0.37)	VEGFAEGLN1MAPTTP53MEN1
	SCHEMBL14809992	0.76	KDM4E (0.44)	VEGFAEGLN1MAPTTP53MEN1
	SCHEMBL14810427	0.76	MAPT (0.39)	VEGFAEGLN1MAPTTP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.