SCHEMBL1480974

SCHEMBL1480974

CCCCCCCCCCCCCCCCCCCC(=O)NC(CO)C(O)CCCCCCCCCCCCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
ASAH1 Q13510 1/20 0.75
DEGS1 O15121 2/20 0.74
PLA2G4A P47712 2/20 0.64
CETP P11597 4/20 0.59
THRB P10828 1/20 0.59
FAAH O00519 2/20 0.54
MAPK1 P28482 1/20 0.54
NOD1 Q9Y239 1/20 0.49
PLA2G2C Q5R387 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6657556 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL7897402 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL6657795 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL6658369 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL21660329 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL22910990 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL21581283 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL22911004 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL21581286 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL21428456 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110077309-A1 HUMECTANT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-03-31 US claimed
US-20240197610-A1 CERAMIDE GROWTH PROMOTING AGENT TAKASAGO INTERNATIONAL CORPORATION (JP) 2024-06-20 US disclosed
EP-4119196-A1 CERAMIDE GROWTH PROMOTING AGENT Takasago International Corporation (JP) 2023-01-18 EP disclosed
CN-115243666-A Ceramide proliferation promoter 高砂香料工业株式会社 2022-10-25 CN disclosed
EP-1633313-B1 LIPID COMPOSITION AND SKIN CARE FORMULATION CONTAINING THE SAME TAKASAGO PERFUMERY CO LTD (JP) 2016-12-07 EP disclosed
US-8865191-B2 Lipid composition and skin care formulation containing the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-10-21 US disclosed
US-8313755-B2 Long-chain fatty acid having 12 to 24 carbon atoms, a nonionic surface active agent; cosmetics, bath agents, hair-care products, external preparations for the skin TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-11-20 US disclosed
EP-1153595-B1 Clear aqueous ceramide composition TAKASAGO PERFUMERY CO LTD (JP) 2012-08-29 EP disclosed
US-20110077309-A1 HUMECTANT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-03-31 US disclosed
EP-1946743-A2 Humectant Composition Takasago International Corporation (JP) 2008-07-23 EP disclosed
US-20080171794-A1 HUMECTANT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-07-17 US disclosed
US-20060210522-A1 Lipid composition and skin care formulation containing the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-09-21 US disclosed
EP-1633313-A1 LIPID COMPOSITION AND SKIN CARE FORMULATION CONTAINING THE SAME Takasago International Corporation (JP) 2006-03-15 EP disclosed
WO-2004098557-A1 LIPID COMPOSITION AND SKIN CARE FORMULATION CONTAINING THE SAME TAKASAGO INTERNATIONAL CORPORATION (FR) 2004-11-18 WO disclosed
US-20020010215-A1 Clear aqueous ceramide composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-01-24 US disclosed
EP-1153595-A2 Clear aqueous ceramide composition Takasago International Corporation (JP) 2001-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060210522-A1 Lipid composition and skin care formulation containing the same CERT1, SGMS1, CERS2 MEN1 2333/4885KMT2A 3033/4885ASAH1 13/4885
US-20240197610-A1 CERAMIDE GROWTH PROMOTING AGENT SGMS1, CERT1, SGMS2 MEN1 867/4885KMT2A 2813/4885ASAH1 27/4885
US-20110077309-A1 HUMECTANT COMPOSITION HSPH1, HOGA1, HMOX2 MEN1 3367/4885KMT2A 3617/4885ASAH1 197/4885
US-20020010215-A1 Clear aqueous ceramide composition CERS2, CERT1, SGMS1 MEN1 3473/4885KMT2A 3379/4885ASAH1 7/4885
US-20080171794-A1 HUMECTANT COMPOSITION HSPH1, HOGA1, HMOX2 MEN1 3367/4885KMT2A 3617/4885ASAH1 197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.