Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9110123 | 0.80 | MAOA (0.57) | MAPTGAALRRK2TDP1HDAC4 | |
| SCHEMBL11202707 | 0.76 | PDE3B (0.51) | ALDH1A1MAPTLRRK2CES1TGM2 | |
| SCHEMBL7828465 | 0.76 | TLK2 (0.63) | LRRK2CHEK1MAP2K1 | |
| SCHEMBL7828461 | 0.76 | TLK2 (0.63) | LRRK2CHEK1MAP2K1 | |
| Hydrochloric Acid SCHEMBL11214501 | 0.75 | PDE3B (0.50) | ALDH1A1MAPTLRRK2CES1TGM2 | |
| SCHEMBL11121469 | 0.74 | HDAC4 (0.58) | ALDH1A1MAPTTDP1HDAC4HDAC2 | |
| SCHEMBL29002763 | 0.74 | HDAC4 (0.58) | ALDH1A1MAPTTDP1HDAC4HDAC2 | |
| SCHEMBL1480120 | 0.74 | HDAC4 (0.58) | ALDH1A1MAPTTDP1HDAC4HDAC2 | |
| SCHEMBL281586 | 0.74 | CES1 (0.55) | ALDH1A1MAPTTDP1CHEK1CES1 | |
| SCHEMBL30397534 | 0.74 | CES1 (0.55) | ALDH1A1MAPTTDP1CHEK1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140378451-A1 | Cannabinoid-2-Receptor Agonists | ISIS INNOVATION LIMITED (GB) | 2014-12-25 | — | — | US | disclosed |
| US-20140378451-A1 | Cannabinoid-2-Receptor Agonists | ISIS INNOVATION LIMITED (GB) | 2014-12-25 | — | — | US | disclosed |
| US-20140378451-A1 | Cannabinoid-2-Receptor Agonists | ISIS INNOVATION LIMITED (GB) | 2014-12-25 | — | — | US | disclosed |
| EP-2766022-A1 | CANNABINOID-2-RECEPTOR AGONISTS | Isis Innovation Limited (GB) | 2014-08-20 | — | — | EP | disclosed |
| WO-2013041859-A1 | CANNABINOID-2-RECEPTOR AGONISTS | ISIS INNOVATION LIMITED (GB) | 2013-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378451-A1 | Cannabinoid-2-Receptor Agonists | CNR2, CNR1, GPR18 | ALDH1A1 3689/4885MAPT 2084/4885TTR 4610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.