Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4940733 | 0.85 | DGAT1 (0.41) | — | |
| SCHEMBL4480678 | 0.78 | SLC6A4 (0.40) | SLC6A4HTR6HTR2CHTR2BMMP13 | |
| SCHEMBL4483839 | 0.73 | S1PR1 (0.36) | SLC6A4 | |
| SCHEMBL14813186 | 0.64 | DGAT1 (0.45) | SLC6A4HTR2CHTR2B | |
| SCHEMBL27769664 | 0.63 | FASN (0.35) | — | |
| SCHEMBL4330968 | 0.59 | PRMT5 (0.44) | SLC6A4HTR2CHTR2B | |
| SCHEMBL4478774 | 0.59 | FASN (0.31) | — | |
| SCHEMBL4065138 | 0.56 | HTR2C (0.63) | HTR2C | |
| SCHEMBL4492585 | 0.55 | NOTUM (0.36) | — | |
| SCHEMBL4474532 | 0.55 | CHEK1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2117526-B1 | INHIBITORS OF DIACYLGLYCEROL O-ACYLTRANSFERASE TYPE 1 ENZYME | ABBOTT LAB (US) | 2013-04-03 | — | — | EP | disclosed |