Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.39 |
| ▸ | LIPE | Q05469 | 4/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14814936 | 0.91 | LIPE (0.39) | P2RX7LIPEPRCPOXTR | |
| SCHEMBL14815461 | 0.83 | LIPE (0.41) | LIPE | |
| SCHEMBL14815136 | 0.82 | LIPE (0.42) | LIPEMGLLPRCPOXTR | |
| SCHEMBL14814935 | 0.82 | NTRK1 (0.34) | P2RX7LIPEPRCP | |
| SCHEMBL14815233 | 0.80 | PKM (0.39) | LIPE | |
| SCHEMBL14814700 | 0.79 | KDM4E (0.44) | — | |
| SCHEMBL14815116 | 0.79 | MGLL (0.42) | P2RX7LIPEMGLL | |
| SCHEMBL14815272 | 0.79 | CCR3 (0.40) | — | |
| SCHEMBL14815376 | 0.78 | LIPE (0.38) | LIPEPRCP | |
| SCHEMBL14815238 | 0.78 | MAPT (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130085142-A1 | SUBSTITUTED OCTAHYDROPYRROLO[1,2-a]PYRAZINES AS CALCIUM CHANNEL BLOCKERS | ABBVIE INC. (US) | 2013-04-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085142-A1 | SUBSTITUTED OCTAHYDROPYRROLO[1,2-a]PYRAZINES AS CALCIUM CHANNEL BLOCKERS | CACNA1C, CACNA1E, CACNA1D | P2RX7 234/4885LIPE 4720/4885MGLL 4703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.