Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.49 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.49 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.49 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.49 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14784048 | 0.87 | RXRA (0.54) | NPC1RAB9ACYP1A1CYP1A2CYP2E1 | |
| SCHEMBL14784175 | 0.86 | NPC1 (0.52) | NPC1RAB9ACYP1A1CYP1A2CYP2E1 | |
| SCHEMBL14879920 | 0.78 | RXRA (0.54) | NPC1RAB9ACYP1A1CYP1A2CYP2E1 | |
| SCHEMBL1689634 | 0.77 | CYP1A1 (0.56) | NPC1RAB9ACYP1A1CYP1A2CYP2E1 | |
| SCHEMBL14898342 | 0.77 | ERN1 (0.54) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL15624598 | 0.76 | NFE2L2 (0.59) | NPC1RAB9ACYP1A1CYP1A2CYP2E1 | |
| SCHEMBL18970413 | 0.75 | CYP1A1 (0.58) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL15243153 | 0.75 | ALDH1A1 (0.50) | NPC1RAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL1689689 | 0.74 | CYP3A4 (0.56) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL14784565 | 0.74 | ALDH1A1 (0.58) | NPC1RAB9AALDH1A1RELAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013037705-A2 | ANILINE DERIVATIVES,THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | FOVEA PHARMACEUTICALS (FR) | 2013-03-21 | — | — | WO | disclosed |