Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 1/20 | 0.72 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.72 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.66 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.60 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | RHEB | Q15382 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 4/20 | 0.58 |
| ▸ | MMP9 | P14780 | 4/20 | 0.58 |
| ▸ | MMP8 | P22894 | 4/20 | 0.58 |
| ▸ | MMP13 | P45452 | 4/20 | 0.58 |
| ▸ | METAP2 | P50579 | 1/20 | 0.56 |
| ▸ | METAP1 | P53582 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20982510 | 0.92 | PKN1 (0.82) | PKN1PKN2CHEK2DGAT1SOAT1 | |
| SCHEMBL3341423 | 0.85 | PKN1 (0.72) | PKN1PKN2CHEK2DGAT1SOAT1 | |
| SCHEMBL18764054 | 0.85 | CHEK2 (0.78) | PKN1PKN2CHEK2DGAT1SOAT1 | |
| SCHEMBL23563056 | 0.83 | PKN1 (0.68) | PKN1PKN2CHEK2DGAT1SOAT1 | |
| SCHEMBL6061287 | 0.81 | PKN1 (0.65) | PKN1PKN2CHEK2DGAT1SOAT1 | |
| SCHEMBL11334567 | 0.80 | PKN1 (0.64) | PKN1PKN2CHEK2DGAT1SOAT1 | |
| SCHEMBL1662880 | 0.79 | MEN1 (0.77) | PKN1PKN2CHEK2DGAT1SOAT1 | |
| SCHEMBL7973324 | 0.79 | PKN1 (0.47) | PKN1PKN2CHEK2DGAT1SOAT1 | |
| SCHEMBL22219469 | 0.78 | PIN1 (0.58) | PKN1PKN2CHEK2DGAT1SOAT1 | |
| SCHEMBL20982791 | 0.78 | PKN1 (0.64) | PKN1PKN2CHEK2DGAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013040527-A1 | ANTIMICROBIAL COMPOUNDS | MICROBIOTIX, INC. (US) | 2013-03-21 | — | — | WO | disclosed |