SCHEMBL14817366

SCHEMBL14817366

COCN(COC)c1nc(-c2ccccc2)nc(N(COC)C(C)O)n1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.37
MEN1 O00255 3/20 0.37
ACP1 P24666 2/20 0.33
L3MBTL1 Q9Y468 5/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 4/20 0.32
PRNP P04156 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
ALDH1A1 P00352 1/20 0.32
BLM P54132 1/20 0.32
TSHR P16473 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PDE5A O76074 1/20 0.32
RECQL P46063 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15363129 0.88 KMT2A (0.38) KMT2AMEN1ACP1L3MBTL1GAA
SCHEMBL14817364 0.87 BCHE (0.32) KMT2AMEN1L3MBTL1MAPTADORA3
SCHEMBL14817377 0.87 RAB9A (0.39) KMT2AMEN1GAAMAPTALDH1A1
SCHEMBL469073 0.86 L3MBTL1 (0.42) KMT2AMEN1ACP1L3MBTL1GAA
SCHEMBL14472261 0.84
SCHEMBL22549081 0.83 L3MBTL1 (0.47) KMT2AMEN1ACP1L3MBTL1GAA
SCHEMBL13140682 0.82 ACP1 (0.37) KMT2AMEN1ACP1L3MBTL1GAA
SCHEMBL14817365 0.82 KMT2A (0.36) KMT2AMEN1ACP1L3MBTL1GAA
SCHEMBL13140683 0.80 L3MBTL1 (0.38) KMT2AMEN1ACP1L3MBTL1GAA
SCHEMBL12198413 0.80 ACP1 (0.48) KMT2AMEN1ACP1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160252834-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-09-01 US disclosed
US-9152120-B2 Cleaning blade, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-10-06 US disclosed
US-9075326-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-07-07 US disclosed
US-9023563-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-05-05 US disclosed
US-8956794-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-02-17 US disclosed
US-8895216-B2 Image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-11-25 US disclosed
US-8822115-B2 Electrophotographic photoreceptor, process cartridge, image forming apparatus, and image forming method FUJI XEROX CO., LTD. (JP) 2014-09-02 US disclosed
US-8822114-B2 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2014-09-02 US disclosed
US-8795934-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-08-05 US disclosed
US-8790854-B2 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2014-07-29 US disclosed
US-20130252148-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-09-26 US disclosed
US-20130252152-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2013-09-26 US disclosed
US-20130244148-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD FUJI XEROX CO., LTD. (JP) 2013-09-19 US disclosed
US-8535861-B2 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2013-09-17 US disclosed
US-8524428-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2013-09-03 US disclosed
US-20130222887-A1 ELECTROPHORETIC PARTICLE, ELECTROPHORETIC PARTICLE DISPERSION LIQUID, DISPLAY MEDIUM, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-08-29 US disclosed
US-8450036-B2 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2013-05-28 US disclosed
US-20130122408-A1 IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-05-16 US disclosed
US-20130101929-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-04-25 US disclosed
US-8404416-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2013-03-26 US disclosed