Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17253259 | 0.92 | LMNA (0.47) | HDAC1HDAC2LMNAEHMT2EHMT1 | |
| SCHEMBL28255049 | 0.87 | HDAC1 (0.48) | HDAC1HDAC2LMNAEHMT2EHMT1 | |
| SCHEMBL3093190 | 0.87 | HDAC1 (0.46) | HDAC1HDAC2LMNAEHMT2EHMT1 | |
| SCHEMBL2738376 | 0.86 | LMNA (0.49) | HDAC1HDAC2LMNAEHMT2EHMT1 | |
| SCHEMBL23336313 | 0.86 | HDAC1 (0.45) | HDAC1HDAC2LMNAEHMT2EHMT1 | |
| SCHEMBL686399 | 0.84 | HDAC1 (0.42) | HDAC1HDAC2LMNAEHMT2EHMT1 | |
| SCHEMBL26553894 | 0.84 | HDAC1 (0.41) | HDAC1HDAC2LMNAEHMT2EHMT1 | |
| SCHEMBL3099655 | 0.83 | HDAC1 (0.47) | HDAC1HDAC2LMNAEHMT2EHMT1 | |
| SCHEMBL24177495 | 0.82 | HDAC1 (0.52) | HDAC1HDAC2LMNASMN1; SMN2 | |
| SCHEMBL10086904 | 0.81 | ALDH1A1 (0.49) | HDAC1HDAC2LMNAEHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404222-B2 | Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution | NEKTAR THERAPEUTICS (US) | 2013-03-26 | — | — | US | disclosed |