Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.46 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14817461 | 0.92 | HDAC1 (0.45) | LMNAEHMT2EHMT1APOBEC3GALDH1A1 | |
| SCHEMBL15777571 | 0.88 | EHMT2 (0.48) | LMNAEHMT2EHMT1APOBEC3GALDH1A1 | |
| SCHEMBL30175601 | 0.87 | LMNA (0.44) | LMNAEHMT2EHMT1APOBEC3GALDH1A1 | |
| SCHEMBL875324 | 0.87 | LMNA (0.44) | LMNAEHMT2EHMT1APOBEC3GALDH1A1 | |
| SCHEMBL21111969 | 0.87 | HDAC1 (0.41) | LMNAEHMT2EHMT1APOBEC3GALDH1A1 | |
| SCHEMBL31040491 | 0.87 | ALDH1A1 (0.49) | LMNAEHMT2EHMT1APOBEC3GALDH1A1 | |
| SCHEMBL31040490 | 0.87 | ALDH1A1 (0.49) | LMNAEHMT2EHMT1APOBEC3GALDH1A1 | |
| SCHEMBL844408 | 0.87 | EHMT2 (0.47) | LMNAEHMT2EHMT1APOBEC3GALDH1A1 | |
| SCHEMBL903346 | 0.87 | ALDH1A1 (0.49) | LMNAEHMT2EHMT1APOBEC3GALDH1A1 | |
| SCHEMBL20095020 | 0.86 | LMNA (0.45) | LMNAEHMT2EHMT1APOBEC3GALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136808-A1 | CONJUGATES UNDERGOING INTRAMOLECULAR REARRANGEMENTS | ASCENDIS PHARMA A/S (DK) | 2021-07-08 | — | — | WO | disclosed |
| EP-2813512-B1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2021-03-31 | — | — | EP | disclosed |
| EP-3207069-B1 | BIO-REDUCIBLE SELF-ASSEMBLED LIQUID CRYSTALLINE BLOCK COPOLYMER FOR DRUG DELIVERY | UNIV CONNECTICUT (US) | 2021-03-10 | — | — | EP | disclosed |
| US-20210061860-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-03-04 | — | — | US | disclosed |
| US-20210024581-A1 | CONJUGATES CONTAINING HYDROPHILIC SPACER LINKERS | ENDOCYTE INC (US) | 2021-01-28 | — | — | US | disclosed |
| US-10363250-B2 | Folate receptor binding conjugates of antifolates | ENDOCYTE, INC. (US) | 2019-07-30 | — | — | US | disclosed |
| US-20170246314-A1 | Folate Receptor Binding Conjugates of Antifolates | PURDUE RESEARCH FOUNDATION (US) | 2017-08-31 | — | — | US | disclosed |
| US-20170240680-A1 | BIO-REDUCIBLE SELF-ASSEMBLED LIQUID CRYSTALLINE BLOCK COPOLYMER FOR DRUG DELIVERY | UNIVERSITY OF CONNECTICUT | 2017-08-24 | — | — | US | disclosed |
| EP-3091026-A1 | DISULFIDE-LINKED REVERSIBLE TERMINATORS | Centrillion Technology Holdings Corporation (KY) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015168809-A1 | POLYGLYOXYLATES, MANUFACTURE AND USE THEREOF | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2015-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210061860-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | VIP, NGLY1, GLP1R | LMNA 2193/4885EHMT2 4765/4885EHMT1 4755/4885 |
| US-20210024581-A1 | CONJUGATES CONTAINING HYDROPHILIC SPACER LINKERS | CD44, HAVCR2, HCAR1 | LMNA 903/4885EHMT2 3025/4885EHMT1 3384/4885 |
| US-10363250-B2 | Folate receptor binding conjugates of antifolates | FOLR1, FOLR2, DHFR | LMNA 4010/4885EHMT2 2264/4885EHMT1 2280/4885 |
| US-20170246314-A1 | Folate Receptor Binding Conjugates of Antifolates | FOLR1, FOLR2, DHFR | LMNA 4010/4885EHMT2 2264/4885EHMT1 2280/4885 |
| US-20170240680-A1 | BIO-REDUCIBLE SELF-ASSEMBLED LIQUID CRYSTALLINE BLOCK COPOLYMER FOR DRUG DELIVERY | CRYAB, CRYAA, BLVRB | LMNA 2569/4885EHMT2 4712/4885EHMT1 4708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.