Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPIB | P23284 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14817478 | 0.81 | POLQ (0.39) | MTNR1AMTNR1BALDH1A1LMNAFASN | |
| SCHEMBL2754184 | 0.77 | ALDH1A1 (0.45) | MTNR1AMTNR1BHTTALDH1A1LMNA | |
| SCHEMBL14817474 | 0.75 | ALDH1A1 (0.39) | MTNR1AMTNR1BALDH1A1OPRM1OPRL1 | |
| SCHEMBL966680 | 0.73 | OPRM1 (0.51) | MTNR1AMTNR1BHTTALDH1A1LMNA | |
| SCHEMBL14817523 | 0.72 | LMNA (0.42) | MTNR1AMTNR1BHTTALDH1A1LMNA | |
| SCHEMBL13848688 | 0.70 | KMT2A (0.36) | MTNR1AMTNR1BHTTALDH1A1LMNA | |
| SCHEMBL13893223 | 0.69 | ALDH1A1 (0.40) | MTNR1AMTNR1BALDH1A1LMNAGLA | |
| SCHEMBL2605743 | 0.69 | ALDH1A1 (0.54) | ALDH1A1LMNAGLATSHRKMT2A | |
| SCHEMBL319608 | 0.69 | KMT2A (0.46) | HTTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL31187018 | 0.68 | NPSR1 (0.47) | MTNR1AMTNR1BHTTALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404846-B2 | Inhibitors of protein tyrosine kinase activity | METHYLGENE INC. (CA) | 2013-03-26 | — | — | US | disclosed |