SCHEMBL14817841

SCHEMBL14817841

CCCn1c(=O)n(CCC)c(=O)n(CCC(C)C)c1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ADORA2A P29274 3/20 0.41
ADORA2B P29275 3/20 0.41
PDE2A O00408 1/20 0.41
PDE1A P54750 1/20 0.41
PDE1B Q01064 1/20 0.41
PDE1C Q14123 1/20 0.41
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
PDE4A P27815 2/20 0.38
PDE4B Q07343 2/20 0.38
PDE4C Q08493 2/20 0.38
PDE4D Q08499 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22625798 1.00 ALDH1A1 (0.46) ALDH1A1TSHRMAPK1SMN1; SMN2ADORA2A
SCHEMBL14802479 0.91 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1SMN1; SMN2ADORA2A
SCHEMBL22753514 0.86 ALDH1A1 (0.46) ALDH1A1TSHRMAPK1SMN1; SMN2ADORA2A
SCHEMBL331903 0.83 PDE4A (0.47) ADORA2AADORA2BPDE4APDE4BPDE4C
SCHEMBL23020227 0.75 GSK3A (0.50) ADORA2AADORA2BPDE4APDE4BPDE4C
SCHEMBL21974369 0.75 GSK3A (0.50) ADORA2AADORA2BPDE4APDE4BPDE4C
SCHEMBL13108310 0.75 PDE4A (0.48) ADORA2AADORA2BPDE4APDE4BPDE4C
SCHEMBL23509686 0.75 RGS4 (0.44) ALDH1A1TSHRSMN1; SMN2ADORA2BLMNA
SCHEMBL24031478 0.73 RGS4 (0.54) ADORA2AADORA2BPDE4APDE4BPDE4C
SCHEMBL30976977 0.73 CSNK2A1 (0.38) ALDH1A1TSHRSMN1; SMN2ADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020202777-A1 EPOXY CURING COMPOUND AND EPOXY RESIN COMPOSITION 堺化学工業株式会社 2020-10-08 WO disclosed
WO-2019034866-A1 BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF Bicyclerd Limited (GB) 2019-02-21 WO disclosed
US-20130079485-A1 SULFUR-CONTAINING POLYUREAS AND METHODS OF USE PRC-DESOTO INTERNATIONAL, INC. (US) 2013-03-28 US disclosed