Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PDE2A | O00408 | 3/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.45 |
| ▸ | PDE1A | P54750 | 1/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22753514 | 0.91 | ALDH1A1 (0.46) | ALDH1A1PDE2AADORA2AADORA2BPDE1A | |
| SCHEMBL22625798 | 0.91 | ALDH1A1 (0.46) | ALDH1A1PDE2AADORA2AADORA2BPDE1A | |
| SCHEMBL14817841 | 0.91 | ALDH1A1 (0.46) | ALDH1A1PDE2AADORA2AADORA2BPDE1A | |
| SCHEMBL16658922 | 0.80 | LMNA (0.39) | ALDH1A1PDE2AADORA2AADORA2BPDE1A | |
| SCHEMBL23509686 | 0.74 | RGS4 (0.44) | ALDH1A1ADORA2BHTTLMNATSHR | |
| SCHEMBL16658929 | 0.74 | RGS4 (0.44) | ALDH1A1PDE2AADORA2AADORA2BPDE1A | |
| SCHEMBL19493548 | 0.74 | CYP3A4 (0.48) | ALDH1A1PDE2AADORA2AADORA2BPDE1A | |
| SCHEMBL10964353 | 0.72 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL18053449 | 0.71 | CYP3A4 (0.57) | ALDH1A1ADORA2AADORA2BHTTSMN1; SMN2 | |
| SCHEMBL20561807 | 0.71 | PDE2A (0.32) | ALDH1A1PDE2AADORA2AADORA2BPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746126-B2 | Bicyclic peptide ligands with detectable moieties and uses thereof | Bicyclerd Limited (GB) | 2023-09-05 | — | — | US | disclosed |
| US-11746126-B2 | Bicyclic peptide ligands with detectable moieties and uses thereof | Bicyclerd Limited (GB) | 2023-09-05 | — | — | US | disclosed |
| US-11241473-B2 | Bicyclic peptide ligands and uses thereof | BICYCLETX LIMITED (GB) | 2022-02-08 | — | — | US | disclosed |
| US-20210147484-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | BICYCLETX LIMITED (GB) | 2021-05-20 | — | — | US | disclosed |
| US-20210079045-A1 | BICYCLIC PEPTIDE LIGANDS WITH DETECTABLE MOIETIES AND USES THEREOF | Bicyclerd Limited (GB) | 2021-03-18 | — | — | US | disclosed |
| US-20210046145-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | BICYCLETX LIMITED (GB) | 2021-02-18 | — | — | US | disclosed |
| US-10919937-B2 | Bicyclic peptide ligands and uses thereof | BICYCLETX LIMITED (GB) | 2021-02-16 | — | — | US | disclosed |
| US-20200347161-A1 | PHOSPHORUS-CONTAINING THERMOPLASTIC POLYMERS | CHEMISCHE FABRIK BUDENHEIM KG (DE) | 2020-11-05 | — | — | US | disclosed |
| WO-2020203540-A1 | CURABLE EPOXY RESIN COMPOSITION | 株式会社ダイセル | 2020-10-08 | — | — | WO | disclosed |
| US-20200291096-A1 | BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF | Bicyclerd Limited (GB) | 2020-09-17 | — | — | US | disclosed |
| US-20200283482-A1 | BICYCLIC PEPTIDE LIGAND PRR-A CONJUGATES AND USES THEREOF | Bicyclerd Limited (GB) | 2020-09-10 | — | — | US | disclosed |
| US-20200131228-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | BICYCLETX LIMITED (GB) | 2020-04-30 | — | — | US | disclosed |
| US-10590264-B2 | Photopolymerization initiator, polymerizable composition, ink jet recording method, and acylphosphine oxide compound | FUJIFILM CORPORATION (JP) | 2020-03-17 | — | — | US | disclosed |
| US-9725556-B2 | Sulfur-containing polyureas and methods of use | PRC-DESOTO INTERNATIONAL, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| US-20150056397-A1 | SULFUR-CONTAINING POLYUREAS AND METHODS OF USE | PRC-DESOTO INTERNATIONAL, INC. | 2015-02-26 | — | — | US | disclosed |
| US-20130079485-A1 | SULFUR-CONTAINING POLYUREAS AND METHODS OF USE | PRC-DESOTO INTERNATIONAL, INC. (US) | 2013-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131228-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | VIP, NGLY1, BID | ALDH1A1 4861/4885PDE2A 3560/4885ADORA2A 3336/4885 |
| US-20200291096-A1 | BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF | STING1, BID, VIP | ALDH1A1 4871/4885PDE2A 1666/4885ADORA2A 1318/4885 |
| US-20210046145-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | VIP, NGLY1, BID | ALDH1A1 4861/4885PDE2A 3560/4885ADORA2A 3336/4885 |
| US-11746126-B2 | Bicyclic peptide ligands with detectable moieties and uses thereof | VIP, NGLY1, GRPR | ALDH1A1 4676/4885PDE2A 3354/4885ADORA2A 3964/4885 |
| US-20210147484-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | VIP, NGLY1, BID | ALDH1A1 4861/4885PDE2A 3560/4885ADORA2A 3336/4885 |
| US-10919937-B2 | Bicyclic peptide ligands and uses thereof | VIP, NGLY1, BID | ALDH1A1 4861/4885PDE2A 3560/4885ADORA2A 3336/4885 |
| US-20210079045-A1 | BICYCLIC PEPTIDE LIGANDS WITH DETECTABLE MOIETIES AND USES THEREOF | VIP, NGLY1, GRPR | ALDH1A1 4676/4885PDE2A 3354/4885ADORA2A 3964/4885 |
| US-10590264-B2 | Photopolymerization initiator, polymerizable composition, ink jet recording method, and acylphosphine oxide compound | CCNT1, CDK1, CCNB1 | ALDH1A1 2338/4885PDE2A 4414/4885ADORA2A 3588/4885 |
| US-20200283482-A1 | BICYCLIC PEPTIDE LIGAND PRR-A CONJUGATES AND USES THEREOF | PRRC2A, GRPR, QRFPR | ALDH1A1 3405/4885PDE2A 3321/4885ADORA2A 730/4885 |
| US-11241473-B2 | Bicyclic peptide ligands and uses thereof | VIP, NGLY1, BID | ALDH1A1 4861/4885PDE2A 3560/4885ADORA2A 3336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.