Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20752666 | 0.91 | SMN1; SMN2 (0.44) | SMN1; SMN2HPGDHTTALDH1A1TDP1 | |
| SCHEMBL20752871 | 0.91 | SMN1; SMN2 (0.44) | SMN1; SMN2HPGDHTTALDH1A1TDP1 | |
| SCHEMBL16784579 | 0.90 | DRD2 (0.42) | SMN1; SMN2HPGDHTTALDH1A1TDP1 | |
| SCHEMBL16784578 | 0.90 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDHTTALDH1A1TDP1 | |
| SCHEMBL12628925 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDHTTALDH1A1TDP1 | |
| SCHEMBL15786508 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDHTTALDH1A1DRD2 | |
| SCHEMBL24686922 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDHTTDRD2KMT2A | |
| SCHEMBL13992473 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDHTTALDH1A1DRD2 | |
| SCHEMBL18387998 | 0.85 | HTT (0.41) | SMN1; SMN2HPGDHTTALDH1A1DRD2 | |
| SCHEMBL14728251 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDHTTDRD2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130078188-A1 | ACTIVATABLE CELL PENETRATING PEPTIDES WITH QUENCHED FLUOROPHORES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130078188-A1 | ACTIVATABLE CELL PENETRATING PEPTIDES WITH QUENCHED FLUOROPHORES | APAF1, NGLY1, TAP1 | SMN1; SMN2 4277/4885HPGD 4467/4885HTT 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.