Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2002775 | 0.89 | DCTPP1 (0.35) | ALDH1A1DCTPP1KDM4EMEN1USP2 | |
| SCHEMBL12570878 | 0.89 | DCTPP1 (0.34) | ALDH1A1DCTPP1KDM4EMEN1USP2 | |
| SCHEMBL14819947 | 0.79 | PPARD (0.38) | ALDH1A1DCTPP1MEN1KMT2APPARG | |
| SCHEMBL2008340 | 0.77 | DCTPP1 (0.35) | ALDH1A1DCTPP1MEN1MAPTKMT2A | |
| SCHEMBL2005624 | 0.73 | PTGDR (0.46) | — | |
| SCHEMBL2003153 | 0.69 | PPARD (0.39) | ALDH1A1DCTPP1MEN1MAPTKMT2A | |
| SCHEMBL3641599 | 0.69 | PPARD (0.39) | ALDH1A1DCTPP1MEN1MAPTKMT2A | |
| SCHEMBL2003491 | 0.66 | CHEK1 (0.46) | ALDH1A1KDM4EMAPTGAAGFER | |
| SCHEMBL7896877 | 0.65 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AGAAGFER | |
| SCHEMBL2001572 | 0.64 | ALDH1A1 (0.39) | ALDH1A1GAAGFERTLR7ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164828-B1 | COMPOUNDS AS CRTH2 AND/OR PGD2 RECEPTORS MODULATORS AND THEIR USE FOR TREATING ASTHMA AND ALLERGIC INFLAMMATION | AMGEN INC (US) | 2013-03-27 | — | — | EP | disclosed |