Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996930 | 0.91 | GLA (0.52) | GLAALDH1A1MAPK1L3MBTL1DDB1 | |
| SCHEMBL10645182 | 0.86 | ALDH1A1 (0.45) | GLAALDH1A1MAPK1L3MBTL1DDB1 | |
| SCHEMBL11203745 | 0.84 | GLA (0.59) | GLAALDH1A1MAPK1L3MBTL1DDB1 | |
| SCHEMBL16553618 | 0.83 | MTNR1A (0.49) | GLAALDH1A1MAPK1L3MBTL1DDB1 | |
| Hydrochloric Acid SCHEMBL9547727 | 0.80 | ALDH1A1 (0.42) | ALDH1A1DDB1CRBNGAANPC1 | |
| SCHEMBL10758512 | 0.80 | CYP3A4 (0.46) | GLAALDH1A1MAPK1L3MBTL1DDB1 | |
| SCHEMBL18014833 | 0.79 | HCAR2 (0.54) | GLAALDH1A1DDB1CRBNGAA | |
| SCHEMBL841868 | 0.77 | GAA (0.70) | ALDH1A1DDB1CRBNGAACYP3A4 | |
| SCHEMBL13220181 | 0.77 | GAA (0.70) | ALDH1A1DDB1CRBNGAACYP3A4 | |
| SCHEMBL841867 | 0.77 | GAA (0.70) | ALDH1A1DDB1CRBNGAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013041899-A1 | FOLDAMERS CONTAINING CYCLIC GAMMA AMINO ACID RESIDUES, EVENTUALLY ALTERNATING WITH ALPHA- AMINOISOBUTYRIC ACID | UNIVERSITE PARIS-SUD XI (FR) | 2013-03-28 | — | — | WO | disclosed |