Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822091 | 0.80 | GLA (0.55) | CYP3A4CYP2C9CYP2C19DDB1CRBN | |
| SCHEMBL18014833 | 0.79 | HCAR2 (0.54) | CYP3A4CYP2C9CYP2C19DDB1CRBN | |
| SCHEMBL10645182 | 0.78 | ALDH1A1 (0.45) | CYP3A4CYP2C9CYP2C19DDB1CRBN | |
| SCHEMBL7306184 | 0.78 | CYP2C19 (0.48) | CYP3A4CYP2C9CYP2C19GAANPC1 | |
| SCHEMBL7306189 | 0.78 | CYP2C19 (0.48) | CYP3A4CYP2C9CYP2C19GAANPC1 | |
| SCHEMBL10755802 | 0.76 | THRB (0.36) | — | |
| SCHEMBL10759188 | 0.76 | ITGB1 (0.36) | SMN1; SMN2CTSD | |
| SCHEMBL8096746 | 0.75 | CYP3A4 (0.49) | CYP3A4CYP2C9CYP2C19GAANPC1 | |
| SCHEMBL8096744 | 0.75 | CYP3A4 (0.49) | CYP3A4CYP2C9CYP2C19GAANPC1 | |
| SCHEMBL13017759 | 0.74 | CTSB (0.49) | CYP3A4CYP2C9CYP2C19NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4677114-A | REDUCING AMNESIA, TREATMENT OF SENILITY | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |
| US-4677098-A | REDUCING AMNESIA AND TREATING SENILITY | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |