SCHEMBL14822103

SCHEMBL14822103

c1ccc(P(c2ccccc2)c2cc3c(cc2-c2ccc4c(c2P(c2ccccc2)c2ccccc2)CCCC4)CCCC3)cc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 1/20 0.33
METAP2 P50579 1/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16079478 0.85 DRD1 (0.35) DRD1
SCHEMBL3967987 0.79 CYP3A4 (0.35) DRD1KIF11
SCHEMBL2914738 0.73 BCL2L1 (0.34) DRD1
SCHEMBL30664383 0.73 BCL2L1 (0.34) DRD1
SCHEMBL29424782 0.72 DRD1 (0.39) DRD1METAP2KIF11
SCHEMBL665033 0.72 DRD1 (0.39) DRD1METAP2KIF11
SCHEMBL29924184 0.72 DRD1 (0.39) DRD1METAP2KIF11
SCHEMBL9192628 0.71 DRD1 (0.38) DRD1METAP2KIF11
Iodide SCHEMBL9231386 0.71 DRD1 (0.38) DRD1METAP2KIF11
Iodide SCHEMBL9231383 0.71 DRD1 (0.38) DRD1METAP2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9545624-B2 Nickel containing hydrosilylation catalysts and compositions containing the catalysts DOW CORNING CORPORATION (US) 2017-01-17 US disclosed
US-9480977-B2 Ruthenium containing hydrosilylation catalysts and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-11-01 US disclosed
US-9221041-B2 Iridium containing hydrosilylation catalysts and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-12-29 US disclosed
US-20140275329-A1 Ruthenium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts DOW SILICONES CORPORATION 2014-09-18 US disclosed
US-20140231702-A1 Cobalt Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts DOW CORNING CORPORATION 2014-08-21 US disclosed
US-20140206869-A1 Iridium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2014-07-24 US disclosed
US-20140183398-A1 Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2014-07-03 US disclosed
WO-2013043783-A2 COBALT CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-03-28 WO disclosed
WO-2013043787-A2 RUTHENIUM CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-03-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140206869-A1 Iridium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts ILK, ALG8, HIRA DRD1 1641/4885METAP2 4772/4885KIF11 3391/4885
US-20140231702-A1 Cobalt Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts HIRA, CROCC, GYPA DRD1 3629/4885METAP2 4772/4885KIF11 3810/4885
US-20140183398-A1 Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts HIRA, ALG8, CAD DRD1 3940/4885METAP2 4725/4885KIF11 3455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.