SCHEMBL665033

SCHEMBL665033

c1ccc(P(c2ccccc2)c2ccc3c(c2-c2c(P(c4ccccc4)c4ccccc4)ccc4c2CCCC4)CCCC3)cc1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 2/20 0.39
CYP3A4 P08684 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TSHR P16473 1/20 0.37
CES1 P23141 6/20 0.37
BCL2L1 Q07817 1/20 0.36
BAD Q92934 1/20 0.36
KIF11 P52732 1/20 0.36
PARP1 P09874 1/20 0.34
METAP2 P50579 1/20 0.33
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29424782 1.00 DRD1 (0.39) DRD1CYP3A4TDP1TSHRCES1
SCHEMBL29924184 1.00 DRD1 (0.39) DRD1CYP3A4TDP1TSHRCES1
Iodide SCHEMBL9231383 0.98 DRD1 (0.38) DRD1CYP3A4TDP1TSHRCES1
Iodide SCHEMBL9231386 0.98 DRD1 (0.38) DRD1CYP3A4TDP1TSHRCES1
SCHEMBL9192628 0.98 DRD1 (0.38) DRD1CYP3A4TDP1TSHRCES1
SCHEMBL14356045 0.96 DRD1 (0.39) DRD1CYP3A4TDP1TSHRCES1
Carbon Monoxide SCHEMBL9194161 0.92 CES1 (0.36) DRD1CYP3A4TDP1TSHRCES1
SCHEMBL7030489 0.92 BCL2L1 (0.42) DRD1CYP3A4TDP1TSHRCES1
Hydrochloric Acid SCHEMBL9191831 0.91 DRD1 (0.37) DRD1CYP3A4TDP1TSHRCES1
Acetic Acid SCHEMBL30315806 0.91 DRD1 (0.37) DRD1CES1BCL2L1BADMETAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3710422-B1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES SYNGENTA CROP PROTECTION AG (CH) 2026-01-07 EP claimed
US-11053188-B2 Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides SYNGENTA PARTICIPATIONS AG (CH) 2021-07-06 US claimed
US-20200407311-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES SYNGENTA PARTICIPATIONS AG (CH) 2020-12-31 US claimed
EP-2482978-B1 HETEROGENEOUS RHODIUM METAL CATALYSTS UNIV ALBERTA (CA) 2018-05-09 EP claimed
US-8962516-B2 Heterogeneous rhodium metal catalysts THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (US) 2015-02-24 US claimed
US-20130053576-A1 HETEROGENEOUS RHODIUM METAL CATALYSTS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA 2013-02-28 US claimed
US-20100311975-A1 CATIONIC TRANSITION METAL CATALYSTS KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2010-12-09 US claimed
EP-1650207-B1 Process for producing optically active 3-quinuclidinols TAKASAGO PERFUMERY CO LTD (JP) 2007-06-27 EP claimed
US-5922918-A Method for making an optically active diphosphine ligand TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-07-13 US claimed
US-5919962-A CATALYST TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-07-06 US claimed
EP-0839819-A1 Method of preparing optically active diphosphine ligands Takasago International Corporation (JP) 1998-05-06 EP claimed
EP-0781749-A2 Process for producing optically active benzhydrol compounds Takasago International Corporation (JP) 1997-07-02 EP claimed
EP-0479542-B1 A phosphino binaphthyl compound and transition metal complexes thereof TAKASAGO PERFUMERY CO LTD (JP) 1995-11-29 EP claimed
US-5206399-A 2,2'-BIS(DIPHENYLPHOSPHINO)-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BINAPHTHYL AND TRANSITION METAL COMPLEX CONTAINING THE SAME AS LIGAND TAKASAGO INTERNATIONAL CORPORATION (JP) 1993-04-27 US claimed
EP-0479542-A1 A phosphino binaphthyl compound and transition metal complexes thereof Takasago International Corporation (JP) 1992-04-08 EP claimed
JP-4139140-A None JP disclosed
US-20260125363-A1 PROCESSES FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMA (US) 2026-05-07 US disclosed
US-5206399-A 2,2'-BIS(DIPHENYLPHOSPHINO)-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BINAPHTHYL AND TRANSITION METAL COMPLEX CONTAINING THE SAME AS LIGAND TAKASAGO INTERNATIONAL CORPORATION (JP) 1993-04-27 US disclosed
US-5206399-A 2,2'-BIS(DIPHENYLPHOSPHINO)-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BINAPHTHYL AND TRANSITION METAL COMPLEX CONTAINING THE SAME AS LIGAND TAKASAGO INTERNATIONAL CORPORATION (JP) 1993-04-27 US disclosed
JP-H04139140-A 2,2'-BIS(DIPHENYLPHOSPHINO)-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BINAPHTHYL AND TRANSITION METALLIC COMPLEX CONTAINING THE SAME AS LIGAND TAKASAGO INTERNATL CORP 1992-05-13 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125363-A1 PROCESSES FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CFTR, SLC26A4, SLC26A3 DRD1 350/4885CYP3A4 2604/4885TDP1 3069/4885
US-20130053576-A1 HETEROGENEOUS RHODIUM METAL CATALYSTS RRM2, RRM2B, RRS1 DRD1 1907/4885CYP3A4 2854/4885TDP1 1474/4885
US-20200407311-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES TBCB, ADORA2B, ADRA2B DRD1 298/4885CYP3A4 418/4885TDP1 4095/4885
US-20100311975-A1 CATIONIC TRANSITION METAL CATALYSTS AP2M1, OPRM1, CD81 DRD1 1797/4885CYP3A4 4218/4885TDP1 2120/4885
US-11053188-B2 Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides TBCB, ADORA2B, CCNB3 DRD1 158/4885CYP3A4 519/4885TDP1 3996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.