Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 3/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | CCR10 | P46092 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639392 | 0.91 | LMNA (0.52) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL21327770 | 0.91 | LMNA (0.52) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL16284421 | 0.86 | LMNA (0.48) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL21327768 | 0.86 | LMNA (0.48) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL14822584 | 0.86 | LMNA (0.48) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL26657822 | 0.86 | CYP2C19 (0.48) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL18823119 | 0.81 | LMNA (0.49) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL9441389 | 0.79 | LMNA (0.50) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL13942277 | 0.78 | KMT2A (0.45) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL8530813 | 0.76 | LMNA (0.59) | LMNATHRBCYP2C19KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759538-B1 | RADIOACTIVE FLUORINE LABELED COMPOUND | NIHON MEDIPHYSICS CO LTD (JP) | 2016-03-23 | — | — | EP | disclosed |
| EP-2759538-A1 | RADIOACTIVE FLUORINE LABELED COMPOUND | Nihon Medi-Physics Co., Ltd. (JP) | 2014-07-30 | — | — | EP | disclosed |
| WO-2013042668-A1 | RADIOACTIVE FLUORINE LABELED COMPOUND | 日本メジフィジックス株式会社 (JP) | 2013-03-28 | — | — | WO | disclosed |