Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.45 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409930 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EGAAMEN1KMT2A | |
| SCHEMBL3678934 | 0.78 | KDM4E (0.48) | SMN1; SMN2KDM4EGAAMEN1KMT2A | |
| SCHEMBL3678936 | 0.78 | KDM4E (0.48) | SMN1; SMN2KDM4EGAAMEN1KMT2A | |
| SCHEMBL23280913 | 0.73 | HTT (0.56) | NPC1RAB9ANAMPTHTTALDH1A1 | |
| SCHEMBL12225791 | 0.73 | SMN1; SMN2 (0.68) | SMN1; SMN2KDM4EGAAMEN1KMT2A | |
| SCHEMBL8819957 | 0.73 | RAB9A (0.70) | SMN1; SMN2KDM4EGAAMEN1KMT2A | |
| SCHEMBL15056922 | 0.72 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EGAAMEN1KMT2A | |
| SCHEMBL17660205 | 0.71 | NPC1 (0.62) | SMN1; SMN2KDM4EGAAMEN1KMT2A | |
| SCHEMBL7717483 | 0.70 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EGAAMEN1KMT2A | |
| SCHEMBL14822906 | 0.70 | MMP2 (0.60) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |