Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.60 |
| ▸ | MMP9 | P14780 | 3/20 | 0.60 |
| ▸ | MMP12 | P39900 | 3/20 | 0.60 |
| ▸ | MMP14 | P50281 | 1/20 | 0.60 |
| ▸ | MMP15 | P51511 | 1/20 | 0.60 |
| ▸ | MMP16 | P51512 | 1/20 | 0.60 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23280913 | 0.87 | HTT (0.56) | HTT | |
| SCHEMBL13409972 | 0.85 | MMP2 (0.50) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL14822984 | 0.80 | LMNA (0.54) | MMP2MMP9MMP12MMP14MMP15 | |
| Trifluoroacetic Acid SCHEMBL3679506 | 0.80 | MMP2 (0.44) | MMP2MMP9MMP12MMP14MMP15 | |
| Trifluoroacetic Acid SCHEMBL3679509 | 0.78 | MMP2 (0.43) | MMP2MMP9MMP12MMP14MMP15 | |
| Trifluoroacetic Acid SCHEMBL3679514 | 0.78 | MMP2 (0.43) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL14823051 | 0.77 | PLK1 (0.58) | HTT | |
| SCHEMBL13245474 | 0.77 | GAA (0.57) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL15146792 | 0.77 | HTT (0.68) | HTT | |
| SCHEMBL3687172 | 0.76 | CRAT (0.49) | MMP2MMP9MMP12MMP14MMP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |