Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | MMP15 | P51511 | 1/20 | 0.44 |
| ▸ | MMP16 | P51512 | 1/20 | 0.44 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409928 | 0.87 | ALDH1A1 (0.51) | LMNAL3MBTL1KDM4EALDH1A1MMP2 | |
| SCHEMBL14822942 | 0.81 | POLB (0.56) | LMNAL3MBTL1KDM4EALDH1A1MMP2 | |
| SCHEMBL14822906 | 0.80 | MMP2 (0.60) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL3683757 | 0.79 | ALDH1A1 (0.49) | LMNAL3MBTL1KDM4EALDH1A1ACACB | |
| SCHEMBL3683754 | 0.79 | ALDH1A1 (0.49) | LMNAL3MBTL1KDM4EALDH1A1ACACB | |
| SCHEMBL13444482 | 0.76 | TAS1R3 (0.37) | ALDH1A1MMP2MMP9TAS1R3TAS1R1 | |
| SCHEMBL14823020 | 0.76 | TAS1R3 (0.68) | LMNAL3MBTL1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL13410038 | 0.74 | CPT2 (0.50) | ACACBFFAR1SUCNR1 | |
| SCHEMBL15623140 | 0.72 | KDM4E (0.52) | LMNAL3MBTL1KDM4EALDH1A1PTGES | |
| SCHEMBL14822999 | 0.72 | SMN1; SMN2 (0.59) | LMNAALDH1A1POLBTP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |