Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.60 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409933 | 0.87 | LTA4H (0.57) | LTA4HNOX1RAB9ASMN1; SMN2NPC1 | |
| Acetic Acid SCHEMBL3681912 | 0.85 | LTA4H (0.55) | LTA4HNOX1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14823033 | 0.85 | CYP2C9 (0.64) | LTA4HRAB9ASMN1; SMN2NPC1PKM | |
| Acetic Acid SCHEMBL3681914 | 0.84 | LTA4H (0.53) | LTA4HNOX1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4738368 | 0.83 | LTA4H (0.65) | LTA4HNOX1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4738358 | 0.83 | LTA4H (0.65) | LTA4HNOX1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14823052 | 0.81 | S1PR1 (0.64) | PKM | |
| SCHEMBL14822987 | 0.81 | PKM (0.54) | RAB9ASMN1; SMN2NPC1PKMALDH1A1 | |
| SCHEMBL21295527 | 0.79 | MEN1 (0.77) | LTA4HNOX1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14070079 | 0.79 | NOX1 (0.58) | LTA4HNOX1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |