Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822898 | 0.86 | ALDH1A1 (0.58) | PKMMEN1KMT2ATAAR1RAB9A | |
| SCHEMBL5404692 | 0.86 | FPR2 (0.51) | ROCK2ROCK1CASRRORCSLC1A3 | |
| SCHEMBL5404682 | 0.86 | FPR2 (0.51) | ROCK2ROCK1CASRRORCSLC1A3 | |
| SCHEMBL14823033 | 0.85 | CYP2C9 (0.64) | PKMUTS2RRAB9ANPC1ALDH1A1 | |
| SCHEMBL13409936 | 0.85 | ROCK2 (0.47) | PKMROCK2ROCK1CASRRORC | |
| SCHEMBL2317343 | 0.84 | ROCK2 (0.65) | ROCK2ROCK1 | |
| SCHEMBL2312556 | 0.84 | ROCK2 (0.65) | ROCK2ROCK1 | |
| SCHEMBL14823053 | 0.83 | FFAR1 (0.48) | PKMROCK2ROCK1MEN1KMT2A | |
| SCHEMBL6375568 | 0.81 | PKM (0.66) | PKMMEN1KMT2ATAAR1RAB9A | |
| SCHEMBL14822985 | 0.81 | LTA4H (0.60) | PKMMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |