SCHEMBL14823602

SCHEMBL14823602

NCCCCCO[C@]1(C(=O)O)C[C@@H](O)[C@@H](O)C([C@H](O)CO)O1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SIGLEC7 Q9Y286 3/20 0.32
▸ NANP Q8TBE9 1/20 0.31
▸ MANBA O00462 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ THRB P10828 1/20 0.30
▸ HIF1A Q16665 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30
▸ CD22 P20273 2/20 0.30
▸ MAG P20916 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15965909 1.00 SIGLEC7 (0.32) SIGLEC7NANPMANBALMNATHRB
SCHEMBL14812005 1.00 SIGLEC7 (0.32) SIGLEC7NANPMANBALMNATHRB
SCHEMBL14823609 0.91 MANBA (0.33) NANPMANBALMNATHRBHIF1A
SCHEMBL15965915 0.91 MANBA (0.33) NANPMANBALMNATHRBHIF1A
SCHEMBL14823596 0.86 CD22 (0.31) NANPMANBALMNATHRBHIF1A
SCHEMBL15965921 0.86 CD22 (0.31) NANPMANBALMNATHRBHIF1A
SCHEMBL15966435 0.84 L3MBTL1 (0.35) SIGLEC7NANPMANBALMNATHRB
SCHEMBL15965910 0.83 SIGLEC7 (0.38) SIGLEC7CD22MAG
SCHEMBL15965861 0.83 SIGLEC7 (0.38) SIGLEC7CD22MAG
SCHEMBL14823604 0.83 SIGLEC7 (0.38) SIGLEC7CD22MAG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150238597-A1 CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-08-27 — — US disclosed
US-20150238597-A1 CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-08-27 — — US disclosed
US-20140234364-A1 TOTAL SYNTHESIS AND IMMUNOLOGICAL EVALUATION OF SACCHARIDE MOIETIES OF THE LIPOPOLYSACCHARIDE FROM NEISSERIA MENINGITIDIS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2014-08-21 — — US disclosed
US-20140234364-A1 TOTAL SYNTHESIS AND IMMUNOLOGICAL EVALUATION OF SACCHARIDE MOIETIES OF THE LIPOPOLYSACCHARIDE FROM NEISSERIA MENINGITIDIS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2014-08-21 — — US disclosed
WO-2013041732-A1 TOTAL SYNTHESIS AND IMMUNOLOGICAL EVALUATION OF SACCHARIDE MOIETIES OF THE LIPOPOLYSACCHARIDE FROM NEISSERIA MENINGITIDIS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2013-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150238597-A1 CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES STT3B, STT3A, DDOST SIGLEC7 12/4885NANP 92/4885MANBA 37/4885
US-20140234364-A1 TOTAL SYNTHESIS AND IMMUNOLOGICAL EVALUATION OF SACCHARIDE MOIETIES OF THE LIPOPOLYSACCHARIDE FROM NEISSERIA MENINGITIDIS FUT5, DAD1, STT3B SIGLEC7 56/4885NANP 110/4885MANBA 82/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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