Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | ABL1 | P00519 | 11/20 | 0.62 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664440 | 0.91 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2ABL1PIK3CA | |
| SCHEMBL4496509 | 0.90 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2ABL1PIK3CA | |
| SCHEMBL13798160 | 0.89 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2ABL1PIK3CA | |
| SCHEMBL2792336 | 0.86 | ABL1 (0.50) | NPC1RAB9ASMN1; SMN2ABL1ACP1 | |
| SCHEMBL2815755 | 0.84 | MMP3 (0.52) | NPC1RAB9ASMN1; SMN2ABL1 | |
| Potassium Ion SCHEMBL2791883 | 0.84 | ABL1 (0.48) | NPC1RAB9ASMN1; SMN2ABL1PIK3CA | |
| SCHEMBL13798182 | 0.83 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2ABL1PIK3CA | |
| SCHEMBL14189671 | 0.83 | ABL1 (0.70) | NPC1RAB9ASMN1; SMN2ABL1PIK3CA | |
| SCHEMBL15259988 | 0.81 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2ABL1PIK3CA | |
| SCHEMBL3664536 | 0.81 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2ABL1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231653-B1 | ANTIBACTERIAL CONDENSED THIAZOLES | BIOTA EUROPE LTD (GB) | 2013-04-03 | — | — | EP | disclosed |