Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HPD | P32754 | 2/20 | 0.41 |
| ▸ | PARG | Q86W56 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15929652 | 1.00 | MAPT (0.46) | MAPTSMN1; SMN2LMNANPSR1L3MBTL1 | |
| SCHEMBL14826600 | 0.92 | HPD (0.47) | MAPTSMN1; SMN2LMNANPSR1L3MBTL1 | |
| SCHEMBL15929629 | 0.92 | GAA (0.47) | MAPTSMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL15929630 | 0.91 | GAA (0.46) | MAPTSMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL15929649 | 0.85 | HTT (0.57) | MAPTSMN1; SMN2L3MBTL1HTTKMT2A | |
| SCHEMBL15082037 | 0.82 | PGR (0.53) | SMN1; SMN2L3MBTL1KMT2AMEN1HPD | |
| SCHEMBL14826593 | 0.82 | HTT (0.53) | MAPTSMN1; SMN2L3MBTL1HTTKMT2A | |
| SCHEMBL15929651 | 0.80 | HTT (0.56) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL14826597 | 0.78 | HTT (0.49) | MAPTSMN1; SMN2L3MBTL1HTTKMT2A | |
| SCHEMBL15929647 | 0.77 | HTT (0.47) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130085251-A1 | POLYMERS AND COPOLYMERS CONTAINING 2H-BENZIMIDAZOL-2-ONE MOIETIES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY (CA) | 2013-04-04 | — | — | US | disclosed |