Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 8/20 | 0.62 |
| ▸ | HEXA | P06865 | 3/20 | 0.61 |
| ▸ | HEXB | P07686 | 3/20 | 0.61 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23957091 | 0.86 | HEXA (0.62) | TERTHEXAHEXBSTAT3HIF1A | |
| SCHEMBL19302158 | 0.84 | TERT (0.56) | TERTHEXAHEXBSTAT3HIF1A | |
| SCHEMBL34460908 | 0.83 | TERT (0.65) | TERTHEXAHEXBSTAT3HIF1A | |
| SCHEMBL2744278 | 0.81 | TERT (0.71) | TERTHEXAHEXBSTAT3HIF1A | |
| SCHEMBL8680446 | 0.81 | TERT (0.67) | TERTSTAT3HIF1AKDM4EMEN1 | |
| SCHEMBL23417393 | 0.81 | STAT3 (0.58) | TERTHEXAHEXBSTAT3HIF1A | |
| SCHEMBL12174260 | 0.80 | HEXA (0.71) | TERTHEXAHEXBSTAT3HIF1A | |
| SCHEMBL23987359 | 0.80 | STAT3 (0.57) | TERTHEXAHEXBSTAT3HIF1A | |
| SCHEMBL23987283 | 0.80 | STAT3 (0.57) | TERTHEXAHEXBSTAT3HIF1A | |
| SCHEMBL23957078 | 0.80 | STAT3 (0.57) | TERTHEXAHEXBSTAT3HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130085280-A1 | MATERIALS AND METHODS FOR THE PREPARATION OF ANISOTROPICALLY-ORDERED SOLIDS | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, (US) | 2013-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085280-A1 | MATERIALS AND METHODS FOR THE PREPARATION OF ANISOTROPICALLY-ORDERED SOLIDS | KIF23, VIM, INCENP | TERT 910/4885HEXA 4665/4885HEXB 4736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.