SCHEMBL1482802

SCHEMBL1482802

CCc1ccccc1-c1ccc2c(c1)C(=O)c1cc(-c3ccccc3CC)ccc1-2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 6/20 0.55
NPC1 O15118 6/20 0.55
RAB9A P51151 6/20 0.55
SMN1; SMN2 Q16637 5/20 0.55
ALDH1A1 P00352 4/20 0.55
LMNA P02545 3/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
MAPT P10636 3/20 0.55
MAPK1 P28482 3/20 0.55
PTPN1 P18031 3/20 0.51
TRPA1 O75762 1/20 0.49
ATM Q13315 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
APAF1 O14727 1/20 0.47
THRB P10828 1/20 0.47
XBP1 P17861 1/20 0.47
PTBP1 P26599 1/20 0.47
HTT P42858 1/20 0.47
GALK1 P51570 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1481199 0.98 PTPRC (0.58) PTPRCNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL18798552 0.79 NPC1 (0.71) PTPRCNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL11647426 0.78 PTGER1 (0.53) TRPA1KMT2AALOX5APFEN1CSNK2A2
SCHEMBL2044259 0.78 TRPA1 (0.49) PTPRCNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL1480166 0.77 PTPRC (0.55) PTPRCNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL1906811 0.76 TRPA1 (0.48) NPC1RAB9ASMN1; SMN2ALDH1A1LMNA
SCHEMBL12856552 0.76 NPC1 (0.64) PTPRCNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL11236910 0.76 RAB9A (0.67) PTPRCNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL1480878 0.76 PTPRC (0.58) PTPRCNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL10604910 0.76 TRPA1 (0.50) NPC1LMNAL3MBTL1MAPTTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293856-B2 Process for preparing olefin polymer using mixed catalyst MITSUI CHEMICALS, INC. (JP) 2012-10-23 US disclosed
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed