SCHEMBL14829409

SCHEMBL14829409

[c]1nc(-c2ccnc3ccccc23)c(-c2ccc3ccccc3n2)c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.44
TGFBR1 P36897 9/20 0.38
MAPK14 Q16539 4/20 0.38
RAB9A P51151 4/20 0.37
NPC1 O15118 3/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
AR P10275 3/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
GRM4 Q14833 1/20 0.36
IDO1 P14902 1/20 0.35
PDE10A Q9Y233 1/20 0.35
TGFBR2 P37173 1/20 0.34
ABL2 P42684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7018481 0.78 RAB9A (0.39) CYP1A2TGFBR1RAB9ANPC1KDM4E
SCHEMBL5480864 0.78 CYP1A2 (0.58) CYP1A2TGFBR1MAPK14RAB9ANPC1
SCHEMBL6490955 0.77 DUSP4 (0.42) CYP1A2TGFBR1RAB9ANPC1KDM4E
SCHEMBL5906927 0.72 AR (0.40) CYP1A2RAB9ANPC1KDM4EALDH1A1
SCHEMBL9674487 0.72 CYP1A2 (0.48) CYP1A2TGFBR1MAPK14RAB9ANPC1
SCHEMBL2418262 0.71 ITK (0.42) RAB9ANPC1KDM4EALDH1A1HPGD
SCHEMBL7135049 0.70 ILK (0.39) RAB9ANPC1KDM4EALDH1A1HPGD
SCHEMBL15155672 0.70 CYP1A2 (0.41) CYP1A2TGFBR1MAPK14RAB9ANPC1
SCHEMBL7918710 0.69 CYP3A4 (0.53) CYP1A2RAB9ANPC1KDM4EALDH1A1
SCHEMBL28845341 0.69 CYP1A2 (0.46) CYP1A2TGFBR1MAPK14RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2788450-A1 WAVELENGTH CONVERSION MATERIAL AS ENCAPSULATE FOR SOLAR MODULE SYSTEMS TO ENHANCE SOLAR HARVESTING EFFICIENCY Nitto Denko Corporation (JP) 2014-10-15 EP disclosed
EP-2760941-A2 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY Nitto Denko Corporation (JP) 2014-08-06 EP disclosed
WO-2013085607-A1 WAVELENGTH CONVERSION MATERIAL AS ENCAPSULATE FOR SOLAR MODULE SYSTEMS TO ENHANCE SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-06-13 WO disclosed
WO-2013049062-A2 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-04-04 WO disclosed