Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5100877 | 0.78 | BACE1 (0.41) | BACE1ALDH1A1PTGS2ALOX5KDM4E | |
| SCHEMBL2576 | 0.74 | ALDH1A1 (0.60) | ALDH1A1ALOX5NPC1MAPK1HTT | |
| SCHEMBL1371612 | 0.73 | ALDH1A1 (0.46) | BACE1ALDH1A1PTGS2ALOX5MAPK1 | |
| SCHEMBL2451112 | 0.73 | ALDH1A1 (0.50) | BACE1ALDH1A1ALOX5MAPK1 | |
| SCHEMBL3886287 | 0.72 | ALDH1A1 (0.56) | ALDH1A1ALOX5NPC1MAPK1HTT | |
| SCHEMBL2448872 | 0.72 | ALDH1A1 (0.56) | ALDH1A1ALOX5MAPK1 | |
| SCHEMBL25683 | 0.72 | ALDH1A1 (0.56) | ALDH1A1ALOX5MAPK1 | |
| SCHEMBL9334552 | 0.72 | ALDH1A1 (0.56) | ALDH1A1ALOX5MAPK1 | |
| SCHEMBL28993681 | 0.72 | ALDH1A1 (0.56) | ALDH1A1ALOX5NPC1MAPK1HTT | |
| Hydrochloric Acid SCHEMBL28609394 | 0.72 | ALDH1A1 (0.56) | ALDH1A1NPC1MAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2761296-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | Waters Technologies Corporation (US) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013049622-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | WATERS TECHNOLOGIES CORPORATION (US) | 2013-04-04 | — | — | WO | disclosed |