Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14839351 | 0.87 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL18619476 | 0.70 | POLB (0.58) | KMT2AMEN1ALDH1A1MAPK1LMNA | |
| SCHEMBL20901574 | 0.70 | ALDH1A1 (0.59) | ALDH1A1POLB | |
| SCHEMBL15962256 | 0.68 | KDM4E (0.54) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| Salicyluric Acid SCHEMBL570541 | 0.67 | HPGD (0.58) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| Salicyluric Acid SCHEMBL29935452 | 0.67 | HPGD (0.58) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL7325670 | 0.67 | KDM4E (0.61) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL21006308 | 0.67 | USP2 (0.59) | CYP1A2POLB | |
| SCHEMBL14839242 | 0.66 | KDM4E (0.59) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL12562532 | 0.66 | NAAA (0.57) | KMT2AMEN1ALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140234365-A1 | 2-HYDROXYHIPPURIC ACID ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | ALERE SAN DIEGO, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| EP-2750706-A1 | 2-HYDROXYHIPPURIC ACID ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | Alere San Diego, Inc. (US) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013049294-A1 | 2-HYDROXYHIPPURIC ACID ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | ALERE SAN DIEGO, INC. (US) | 2013-04-04 | — | — | WO | disclosed |
| WO-2013049294-A1 | 2-HYDROXYHIPPURIC ACID ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | ALERE SAN DIEGO, INC. (US) | 2013-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140234365-A1 | 2-HYDROXYHIPPURIC ACID ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | SLC3A2, CTH, FABP1 | KMT2A 2015/4885MEN1 3017/4885ALDH1A1 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.