Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.66 |
| ▸ | USP2 | O75604 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | FYN | P06241 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
| ▸ | XIAP | P98170 | 1/20 | 0.59 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.56 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483094 | 1.00 | SLC7A5 (0.66) | SLC7A5USP2HSD17B10ALOX15ADORA3 | |
| SCHEMBL12803446 | 0.87 | SLC7A5 (0.56) | SLC7A5USP2HSD17B10ALOX15ADORA3 | |
| SCHEMBL31524255 | 0.87 | SLC7A5 (0.56) | SLC7A5USP2HSD17B10ALOX15ADORA3 | |
| SCHEMBL10064656 | 0.87 | SLC7A5 (0.56) | SLC7A5USP2HSD17B10ALOX15ADORA3 | |
| SCHEMBL5560750 | 0.87 | SLC7A5 (0.56) | SLC7A5USP2HSD17B10ALOX15ADORA3 | |
| SCHEMBL5560150 | 0.84 | SLC7A5 (0.53) | SLC7A5USP2HSD17B10ALOX15ADORA3 | |
| SCHEMBL5560145 | 0.82 | SLC7A5 (0.50) | SLC7A5USP2HSD17B10ALOX15ADORA3 | |
| SCHEMBL4616523 | 0.82 | HSD17B10 (0.68) | SLC7A5USP2HSD17B10ALOX15ADORA3 | |
| SCHEMBL358292 | 0.82 | HSD17B10 (0.68) | SLC7A5USP2HSD17B10ALOX15ADORA3 | |
| SCHEMBL31453795 | 0.81 | GRIA2 (0.82) | SLC7A5USP2HSD17B10ALOX15ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357654-B2 | Multimeric CD40 ligands, method for preparing same and use thereof for preparing drugs | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-01-22 | — | — | US | claimed |
| US-20100183642-A1 | NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-07-22 | — | — | US | claimed |
| US-20100136034-A1 | NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-06-03 | — | — | US | claimed |
| EP-2114998-A1 | NOVEL MULTIMERIC MOLECULES, METHOD FOR PREPARING SAME AND USE THEREOF IN THE PREPARATION OF DRUGS | Centre National de la Recherche Scientifique (FR) | 2009-11-11 | — | — | EP | claimed |
| EP-1828240-B1 | NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS | CENTRE NAT RECH SCIENT (FR) | 2009-07-29 | — | — | EP | claimed |
| WO-2008110695-A1 | NOVEL MULTIMERIC MOLECULES, METHOD FOR PREPARING SAME AND USE THEREOF IN THE PREPARATION OF DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2008-09-18 | — | — | WO | claimed |
| EP-1828240-A2 | NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS | The Centre National de la Recherche Scientifique (FR) | 2007-09-05 | — | — | EP | claimed |
| WO-2006064133-A2 | NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2006-06-22 | — | — | WO | claimed |
| US-8357654-B2 | Multimeric CD40 ligands, method for preparing same and use thereof for preparing drugs | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-01-22 | — | — | US | disclosed |
| US-8232417-B1 | Artemisinin derivatives with natural amino acids, peptides, and amino sugars for skin imperfections and infection in mammals | BIODERM RESEARCH (US) | 2012-07-31 | — | — | US | disclosed |
| US-20120189567-A1 | Artemisinin Derivatives with Natural Amino Acids, Peptides, and Amino Sugars for Skin Imperfections and Infection in Mammals | BIODERM RESEARCH (US) | 2012-07-26 | — | — | US | disclosed |
| US-8193376-B2 | Artemisinin derivatives with natural amino acids, peptides, and amino sugars for the treatment of infection and topical condition in mammals | BIODERM RESEARCH (US) | 2012-06-05 | — | — | US | disclosed |
| US-20110077193-A1 | Artemisinin Derivatives with Natural Amino Acids, Peptides, and Amino Sugars for the Treatment of Infection and Topical Condition in Mammals | BIODERM RESEARCH (US) | 2011-03-31 | — | — | US | disclosed |
| US-20100183642-A1 | NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-07-22 | — | — | US | disclosed |
| WO-2006064133-A2 | NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2006-06-22 | — | — | WO | disclosed |
| US-6933365-B2 | Mutant tyrosine repressor proteins | AJINOMOTO CO., INC. (JP) | 2005-08-23 | — | — | US | disclosed |
| US-20050089967-A1 | Mutant tyrosine repressor gene and utilization thereof | AJINOMOTO CO., INC. (JP) | 2005-04-28 | — | — | US | disclosed |
| US-20020010136-A1 | Mutant tyrosine repressor gene and utilization thereof | AJINOMOTO CO., INC. (JP) | 2002-01-24 | — | — | US | disclosed |
| EP-0998487-A2 | INCORPORATION OF PHARMACOLOGICALLY ACTIVE AMINO ACID ANALOGUES INTO PROTEINS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2000-05-10 | — | — | EP | disclosed |
| WO-1998056824-A2 | INCORPORATION OF PHARMACOLOGICALLY ACTIVE AMINO ACID ANALOGUES INTO PROTEINS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1998-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120189567-A1 | Artemisinin Derivatives with Natural Amino Acids, Peptides, and Amino Sugars for Skin Imperfections and Infection in Mammals | CUTA, ROS1, RAB35 | SLC7A5 33/4885USP2 4244/4885HSD17B10 1335/4885 |
| US-20100183642-A1 | NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS | CD40, CD40LG, TNFSF10 | SLC7A5 1065/4885USP2 3224/4885HSD17B10 4407/4885 |
| US-20100136034-A1 | NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS | TNFRSF1A, TNFRSF9, CD40 | SLC7A5 1624/4885USP2 3162/4885HSD17B10 3338/4885 |
| US-20110077193-A1 | Artemisinin Derivatives with Natural Amino Acids, Peptides, and Amino Sugars for the Treatment of Infection and Topical Condition in Mammals | CUTA, ATF4, IL17A | SLC7A5 50/4885USP2 4406/4885HSD17B10 1496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.